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Articles (32)

• An efficient method for the synthesis of peptide aldehyde libraries employed in the discovery of reversible SARS coronavirus main protease (SARS-Cov Mpro) inhibitors

  👤 Al-Gharabli, Samer I. 👤 Ali Shah, Syed T. 👤 Weik, Steffen 👤 Schmidt, Marco F. 👤 Mesters, Jeroen R. 👤 Kuhn, Daniel 👤 Klebe, Gerhard 👤 Hilgenfeld, Rolf 👤 Rademann, Jörg ⏰ 2006 📚 ChemBioChem

• High-throughput screening identifies inhibitors of the SARS coronavirus main proteinase

  👤 Blanchard, Jan E. 👤 Elowe, Nadine H. 👤 Huitema, Carly 👤 Fortin, Pascal D. 👤 Cechetto, Jonathan D. 👤 Eltis, Lindsay D. 👤 Brown, Eric D. ⏰ 2004 📚 Chemistry and Biology

• Structure-based virtual screening and experimental validation of the discovery of inhibitors targeted towards the human coronavirus nucleocapsid protein

  👤 Chang, Chung Ke 👤 Jeyachandran, Sivakamavalli 👤 Hu, Nien Jen 👤 Liu, Chia Ling 👤 Lin, Shing Yen 👤 Wang, Yong Sheng 👤 Chang, Yu Ming 👤 Hou, Ming Hon ⏰ 2016 📚 Molecular BioSystems

• Discovering severe acute respiratory syndrome coronavirus 3CL protease inhibitors: Virtual screening, surface plasmon resonance, and fluorescence resonance energy transfer assays

  👤 Chen, Lili 👤 Chen, Shuai 👤 Gui, Chunshan 👤 Shen, Jianhua 👤 Shen, Xu 👤 Jiang, Hualiang ⏰ 2006 📚 Journal of Biomolecular Screening

• Cinanserin is an inhibitor of the 3C-like proteinase of severe acute respiratory syndrome coronavirus and strongly reduces virus replication in vitro

  👤 Chen, Lili 👤 Gui, Chunshan 👤 Luo, Xiaomin 👤 Yang, Qingang 👤 Günther, Stephan 👤 Scandella, Elke 👤 Drosten, Christian 👤 Bai, Donglu 👤 He, Xichang 👤 Ludewig, Burkhard 👤 Chen, Jing 👤 Luo, Haibin 👤 Yang, Yiming 👤 Yang, Yifu 👤 Zou, Jianping 👤 Thiel, Volker 👤 Chen, Kaixian 👤 Shen, Jianhua 👤 Shen, Xu 👤 Jiang, Hualiang ⏰ 2005 📚 Journal of Virology

• Prediction of the SARS-CoV-2 (2019-nCoV) 3C-like protease (3CL (pro)) structure: virtual screening reveals velpatasvir, ledipasvir, and other drug repurposing candidates.

  👤 Chen, Yu Wai 👤 Yiu, Chin-Pang Bennu 👤 Wong, Kwok-Yin ⏰ 2020 📚 F1000Res

• What use are words at a time like this?

  👤 Darbyshire, Philip ⏰ 2020 📚 J Clin Nurs

• A guideline for homology modeling of the proteins from newly discovered betacoronavirus, 2019 novel coronavirus (2019-nCoV).

  👤 Dong, Shengjie 👤 Sun, Jiachen 👤 Mao, Zhuo 👤 Wang, Lu 👤 Lu, Yi-Lin 👤 Li, Jiesen ⏰ 2020 📚 J Med Virol

• Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis

  👤 Hamming, I. 👤 Timens, W. 👤 Bulthuis, M. L.C. 👤 Lely, A. T. 👤 Navis, G. J. 👤 van Goor, H. ⏰ 2004 📚 Journal of Pathology

• Human coronavirus NL63 employs the severe acute respiratory syndrome coronavirus receptor for cellular entry

  👤 Hofmann, Heike 👤 Pyrc, Krzysztof 👤 Van Der Hoek, Lia 👤 Geier, Martina 👤 Berkhout, Ben 👤 Pöhlmann, Stefan ⏰ 2005 📚 Proceedings of the National Academy of Sciences of the United States of America

• A midpoint perspective on the COVID-19 pandemic.

  👤 Hsu, Li Yang 👤 Chia, Po Ying 👤 Vasoo, Shawn ⏰ 2020 📚 Singapore Med J

• Evolution of genomes, host shifts and the geographic spread of SARS-CoV and related coronaviruses

  👤 Janies, Daniel 👤 Habib, Farhat 👤 Alexandrov, Boyan 👤 Hill, Andrew 👤 Pol, Diego ⏰ 2008 📚 Cladistics

• Structure of M(pro) from COVID-19 virus and discovery of its inhibitors.

  👤 Jin, Zhenming 👤 Du, Xiaoyu 👤 Xu, Yechun 👤 Deng, Yongqiang 👤 Liu, Meiqin 👤 Zhao, Yao 👤 Zhang, Bing 👤 Li, Xiaofeng 👤 Zhang, Leike 👤 Peng, Chao 👤 Duan, Yinkai 👤 Yu, Jing 👤 Wang, Lin 👤 Yang, Kailin 👤 Liu, Fengjiang 👤 Jiang, Rendi 👤 Yang, Xinglou 👤 You, Tian 👤 Liu, Xiaoce 👤 Yang, Xiuna 👤 Bai, Fang 👤 Liu, Hong 👤 Liu, Xiang 👤 Guddat, Luke W 👤 Xu, Wenqing 👤 Xiao, Gengfu 👤 Qin, Chengfeng 👤 Shi, Zhengli 👤 Jiang, Hualiang 👤 Rao, Zihe 👤 Yang, Haitao ⏰ 2020 📚 Nature

• Virtual screening and repurposing of FDA approved drugs against COVID-19 main protease.

  👤 Kandeel, Mahmoud 👤 Al-Nazawi, Mohammed ⏰ 2020 📚 Life Sci

• Interpreting COVID-19 and Virtual Care Trends: A Call for Action.

  👤 Khairat, Saif 👤 Meng, Chenlu 👤 Xu, Yuxuan 👤 Edson, Barbara 👤 Gianforcaro, Robert ⏰ 2020 📚 JMIR Public Health Surveill

• Targeting SARS-CoV-2: A Systematic Drug Repurposing Approach to Identify Promising Inhibitors Against 3C-like Proteinase and 2'-O-RiboseMethyltransferase.

  👤 Khan, Rameez Jabeer 👤 Jha, Rajat Kumar 👤 Amera, GizachewMuluneh 👤 Jain, Monika 👤 Singh, Ekampreet 👤 Pathak, Amita 👤 Singh, Rashmi Prabha 👤 Muthukumaran, Jayaraman 👤 Singh, Amit Kumar ⏰ 2020 📚 J Biomol Struct Dyn

• Coronavirus IBV-induced membrane fusion occurs at near-neutral pH

  👤 Li, D. 👤 Cavanagh, D. ⏰ 1992 📚 Archives of Virology

• Structure-Based Stabilization of Non-native Protein-Protein Interactions of Coronavirus Nucleocapsid Proteins in Antiviral Drug Design.

  👤 Lin, Shan-Meng 👤 Lin, Shih-Chao 👤 Hsu, Jia-Ning 👤 Chang, Chung-Ke 👤 Chien, Ching-Ming 👤 Wang, Yong-Sheng 👤 Wu, Hung-Yi 👤 Jeng, U-Ser 👤 Kehn-Hall, Kylene 👤 Hou, Ming-Hon ⏰ 2020 📚 J Med Chem

• Structural basis for the identification of the N-terminal domain of coronavirus nucleocapsid protein as an antiviral target

  👤 Lin, Shing Yen 👤 Liu, Chia Ling 👤 Chang, Yu Ming 👤 Zhao, Jincun 👤 Perlman, Stanley 👤 Hou, Ming Hon ⏰ 2014 📚 Journal of Medicinal Chemistry

• Importance of conserved cysteine residues in the coronavirus envelope protein

  👤 Lopez, Lisa A. 👤 Riffle, Ambere J. 👤 Pike, Steven L. 👤 Gardner, Douglas 👤 Hogue, Brenda G. ⏰ 2008 📚 Journal of Virology

• Structure-based drug design and structural biology study of novel nonpeptide inhibitors of severe acute respiratory syndrome coronavirus main protease

  👤 Lu, I. Lin 👤 Mahindroo, Neeraj 👤 Liang, Po Huang 👤 Peng, Yi Hui 👤 Kuo, Chih Jung 👤 Tsai, Keng Chang 👤 Hsieh, Hsing Pang 👤 Chao, Yu Sheng 👤 Wu, Su Ying ⏰ 2006 📚 Journal of Medicinal Chemistry

• Identification of rna pseudoknot-binding ligand that inhibits the - 1 ribosomal frameshifting of SARS-coronavirus by structure-based virtual screening

  👤 Park, So Jung 👤 Kim, Yang Gyun 👤 Park, Hyun Ju ⏰ 2011 📚 Journal of the American Chemical Society

• A severe acute respiratory syndrome-associated coronavirus-specific protein enhances virulence of an attenuated murine coronavirus

  👤 Pewe, Lecia 👤 Zhou, Haixia 👤 Netland, Jason 👤 Tangudu, Chandra 👤 Olivares, Heidi 👤 Shi, Lei 👤 Look, Dwight 👤 Gallagher, Thomas 👤 Perlman, Stanley ⏰ 2005 📚 Journal of Virology

• An overview of severe acute respiratory syndrome-coronavirus (SARS-CoV) 3CL protease inhibitors: Peptidomimetics and small molecule chemotherapy

  👤 Pillaiyar, Thanigaimalai 👤 Manickam, Manoj 👤 Namasivayam, Vigneshwaran 👤 Hayashi, Yoshio 👤 Jung, Sang Hun ⏰ 2016 📚 Journal of Medicinal Chemistry

• In-silico homology assisted identification of inhibitor of RNA binding against 2019-nCoV N-protein (N terminal domain).

  👤 Sarma, Phulen 👤 Sekhar, Nishant 👤 Prajapat, Manisha 👤 Avti, Pramod 👤 Kaur, Hardeep 👤 Kumar, Subodh 👤 Singh, Sanjay 👤 Kumar, Harish 👤 Prakash, Ajay 👤 Dhibar, Deba Prasad 👤 Medhi, Bikash ⏰ 2020 📚 J Biomol Struct Dyn

• COVID-19: Pandemic Contingency Planning for the Allergy and Immunology Clinic.

  👤 Shaker, Marcus S 👤 Oppenheimer, John 👤 Grayson, Mitchell 👤 Stukus, David 👤 Hartog, Nicholas 👤 Hsieh, Elena W Y 👤 Rider, Nicholas 👤 Dutmer, Cullen M 👤 Vander Leek, Timothy K 👤 Kim, Harold 👤 Chan, Edmond S 👤 Mack, Doug 👤 Ellis, Anne K 👤 Lang, David 👤 Lieberman, Jay 👤 Fleischer, David 👤 Golden, David B K 👤 Wallace, Dana 👤 Portnoy, Jay 👤 Mosnaim, Giselle 👤 Greenhawt, Matthew ⏰ 2020 📚 J Allergy Clin Immunol Pract

• Recent aspects on the pathogenesis mechanism, animal models and novel therapeutic interventions for middle east respiratory syndrome coronavirus infections

  👤 Skariyachan, Sinosh 👤 Challapilli, Sneha Basavaraj 👤 Packirisamy, Swathi 👤 Kumargowda, Supreetha Toplar 👤 Sridhar, Vaishnavi Sneha ⏰ 2019 📚 Frontiers in Microbiology

• Comparison of hemagglutinating, receptor-destroying, and acetylesterase activities of avirulent and virulent bovine coronavirus strains

  👤 Storz, J. 👤 Zhang, X. M. 👤 Rott, R. ⏰ 1992 📚 Archives of Virology

• Custom-made 3D-printed face masks in case of pandemic crisis situations with a lack of commercially available FFP2/3 masks.

  👤 Swennen, Gwen R J 👤 Pottel, Lies 👤 Haers, Piet E ⏰ 2020 📚 Int J Oral Maxillofac Surg

• Rapid Identification of Potential Inhibitors of SARS-CoV-2 Main Protease by Deep Docking of 1.3 Billion Compounds.

  👤 Ton, Anh-Tien 👤 Gentile, Francesco 👤 Hsing, Michael 👤 Ban, Fuqiang 👤 Cherkasov, Artem ⏰ 2020 📚 Mol Inform

• Cleveland Clinic Akron General Urology Residency Program's COVID-19 Experience.

  👤 Vargo, Ethan 👤 Ali, Marwan 👤 Henry, Fabrice 👤 Kmetz, Daniel 👤 Krishnan, Jayram 👤 Bologna, Raymond ⏰ 2020 📚 Urology

• Generation of predictive pharmacophore model for SARS-coronavirus main proteinase

  👤 Zhang, Xue Wu 👤 Yap, Yee Leng 👤 Altmeyer, Ralf M. ⏰ 2005 📚 European Journal of Medicinal Chemistry