π Viral inhibitor
Articles (4)
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Potential broad spectrum inhibitors of the Coronavirus 3CLpro: A virtual screening and structure-based drug design study
π€ Berry, Michael π€ Fielding, Burtram C. π€ Gamieldien, Junaid β° 2015 π Viruses
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Human Coronavirus OC43 Serum Inhibitor and Neutralizing Antibody by a New Plaque-Reduction Assay
π€ Gerna, Giuseppe π€ Cattaneo, Ercole π€ Cereda, Paolo M. π€ Revelo, M. Grazia π€ Achilli, Giorgio β° 1980 π Proceedings of the Society for Experimental Biology and Medicine
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Discovery, synthesis, and structure-based optimization of a series of N -(tert -Butyl)-2-(N -arylamido)-2-(pyridin-3-yl) acetamides (ML188) as potent noncovalent small molecule inhibitors of the severe acute respiratory syndrome coronavirus (SARS-CoV) 3CL protease
π€ Jacobs, Jon π€ Grum-Tokars, Valerie π€ Zhou, Ya π€ Turlington, Mark π€ Saldanha, S. Adrian π€ Chase, Peter π€ Eggler, Aimee π€ Dawson, Eric S. π€ Baez-Santos, Yahira M. π€ Tomar, Sakshi π€ Mielech, Anna M. π€ Baker, Susan C. π€ Lindsley, Craig W. π€ Hodder, Peter π€ Mesecar, Andrew π€ Stauffer, Shaun R. β° 2013 π Journal of Medicinal Chemistry
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P53 down-regulates SARS coronavirus replication and is targeted by the SARS-unique domain and PLpro via E3 ubiquitin ligase RCHY1
π€ Ma-Lauer, Yue π€ Carbajo-Lozoya, Javier π€ Hein, Marco Y. π€ MΓΌller, Marcel A. π€ Deng, Wen π€ Lei, Jian π€ Meyer, Benjamin π€ Kusov, Yuri π€ Von Brunn, Brigitte π€ Bairad, Dev Raj π€ HΓΌnten, Sabine π€ Drosten, Christian π€ Hermeking, Heiko π€ Leonhardt, Heinrich π€ Mann, Matthias π€ Hilgenfeld, Rolf π€ Von Brunn, Albrecht β° 2016 π Proceedings of the National Academy of Sciences of the United States of America