🔗 3c-like proteinase

Articles (24)

• Cinanserin is an inhibitor of the 3C-like proteinase of severe acute respiratory syndrome coronavirus and strongly reduces virus replication in vitro

  👤 Chen, Lili 👤 Gui, Chunshan 👤 Luo, Xiaomin 👤 Yang, Qingang 👤 Günther, Stephan 👤 Scandella, Elke 👤 Drosten, Christian 👤 Bai, Donglu 👤 He, Xichang 👤 Ludewig, Burkhard 👤 Chen, Jing 👤 Luo, Haibin 👤 Yang, Yiming 👤 Yang, Yifu 👤 Zou, Jianping 👤 Thiel, Volker 👤 Chen, Kaixian 👤 Shen, Jianhua 👤 Shen, Xu 👤 Jiang, Hualiang ⏰ 2005 📚 Journal of Virology

• Severe acute respiratory syndrome coronavirus 3C-like proteinase N terminus is indispensable for proteolytic activity but not for enzyme dimerization: Biochemical and thermodynamic investigation in conjunction with molecular dynamics simulations

  👤 Chen, Shuai 👤 Chen, Lili 👤 Tan, Jinzhi 👤 Chen, Jing 👤 Du, Li 👤 Sun, Tao 👤 Shen, Jianhua 👤 Chen, Kaixian 👤 Jiang, Hualiang 👤 Shen, Xu ⏰ 2005 📚 Journal of Biological Chemistry

• The interaction between severe acute respiratory syndrome coronavirus 3C-like proteinase and a dimeric inhibitor by capillary electrophoresis

  👤 Ding, Li 👤 Zhang, Xin Xiang 👤 Wei, Ping 👤 Fan, Keqiang 👤 Lai, Luhua ⏰ 2005 📚 Analytical Biochemistry

• The substrate specificity of SARS coronavirus 3C-like proteinase

  👤 Fan, Keqiang 👤 Ma, Liang 👤 Han, Xiaofeng 👤 Liang, Huanhuan 👤 Wei, Ping 👤 Liu, Ying 👤 Lai, Luhua ⏰ 2005 📚 Biochemical and Biophysical Research Communications

• Biosynthesis, Purification, and Substrate Specificity of Severe Acute Respiratory Syndrome Coronavirus 3C-like Proteinase

  👤 Fan, Keqiang 👤 Wei, Ping 👤 Feng, Qian 👤 Chen, Sidi 👤 Huang, Changkang 👤 Ma, Liang 👤 Lai, Bing 👤 Pei, Jianfeng 👤 Liu, Ying 👤 Chen, Jianguo 👤 Lai, Luhua ⏰ 2004 📚 Journal of Biological Chemistry

• Proteolytic processing of polyproteins 1a and 1ab between non-structural proteins 10 and 11/12 of Coronavirus infectious bronchitis virus is dispensable for viral replication in cultured cells

  👤 Fang, Shou Guo 👤 Shen, Hongyuan 👤 Wang, Jibin 👤 Tay, Felicia P.L. 👤 Liu, Ding Xiang ⏰ 2008 📚 Virology

• Functional and genetic studies of the substrate specificity of coronavirus infectious bronchitis virus 3C-like proteinase

  👤 Fang, Shouguo 👤 Shen, Hongyuan 👤 Wang, Jibin 👤 Tay, Felicia P.L. 👤 Liu, Ding Xiang ⏰ 2010 📚 Journal of Virology

• Prediction of proteinase cleavage sites in polyproteins of coronaviruses and its applications in analyzing SARS-CoV genomes

  👤 Gao, Feng 👤 Ou, Hong Yu 👤 Chen, Ling Ling 👤 Zheng, Wen Xin 👤 Zhang, Chun Ting ⏰ 2003 📚 FEBS Letters

• Identification of the polymerase polyprotein products p72 and p65 of the murine coronavirus MHV-JHM

  👤 Gao, Hong Qiang 👤 Schiller, Jennifer J. 👤 Baker, Susan C. ⏰ 1996 📚 Virus Research

• Characterization of a 105-kDa polypeptide encoded in gene 1 of the human coronavirus HCV 229E

  👤 Grötzinger, Carsten 👤 Heusipp, Gerhard 👤 Ziebuhr, John 👤 Harms, Ute 👤 Süss, Jochen 👤 Siddell, Stuart G. ⏰ 1996 📚 Virology

• 3C-like Proteinase from SARS Coronavirus Catalyzes Substrate Hydrolysis by a General Base Mechanism

  👤 Huang, Changkang 👤 Wei, Ping 👤 Fan, Keqiang 👤 Liu, Ying 👤 Lai, Luhua ⏰ 2004 📚 Biochemistry

• Identification of the murine coronavirus MP1 cleavage site recognized by papain-like proteinase 2

  👤 Kanjanahaluethai, Amornrat 👤 Jukneliene, Dalia 👤 Baker, Susan C. ⏰ 2003 📚 Journal of Virology

• Targeting SARS-CoV-2: A Systematic Drug Repurposing Approach to Identify Promising Inhibitors Against 3C-like Proteinase and 2'-O-RiboseMethyltransferase.

  👤 Khan, Rameez Jabeer 👤 Jha, Rajat Kumar 👤 Amera, GizachewMuluneh 👤 Jain, Monika 👤 Singh, Ekampreet 👤 Pathak, Amita 👤 Singh, Rashmi Prabha 👤 Muthukumaran, Jayaraman 👤 Singh, Amit Kumar ⏰ 2020 📚 J Biomol Struct Dyn

• Maturation mechanism of severe acute respiratory syndrome (SARS) coronavirus 3C-like proteinase

  👤 Li, Chunmei 👤 Qi, Yifei 👤 Teng, Xin 👤 Yang, Zongchang 👤 Wei, Ping 👤 Zhang, Changsheng 👤 Tan, Lei 👤 Zhou, Lu 👤 Liu, Ying 👤 Lai, Luhua ⏰ 2010 📚 Journal of Biological Chemistry

• Identification of a novel cleavage activity of the first papain-like proteinase domain encoded by open reading frame 1a of the coronavirus Avian infectious bronchitis virus and characterization of the cleavage products

  👤 Lim, K. P. 👤 Ng, Lisa F.P. 👤 Liu, D. X. ⏰ 2000 📚 Journal of Virology

• Proteolytic mapping of the coronavirus infectious bronchitis virus lb polyprotein: Evidence for the presence of four cleavage sites of the 3C-like proteinase and identification of two novel cleavage products

  👤 Liu, D. X. 👤 Shen, S. 👤 Xu, H. Y. 👤 Wang, S. F. ⏰ 1998 📚 Virology

• Intracellular and in vitro-translated 27-kDa proteins contain the 3C-like proteinase activity of the coronavirus MHV-A59

  👤 Lu, Xiaotao 👤 Lu, Yiqi 👤 Denison, Mark R. ⏰ 1996 📚 Virology

• Identification of a 24-kDa polypeptide processed from the coronavirus infectious bronchitis virus 1a polyprotein by the 3C-like proteinase and determination of its cleavage sites

  👤 Ng, Lisa F.P. 👤 Liu, D. X. ⏰ 1998 📚 Virology

• Further characterization of the coronavirus infectious bronchitis virus 3C-like proteinase and determination of a new cleavage site

  👤 Ng, Lisa F.P. 👤 Liu, D. X. ⏰ 2000 📚 Virology

• Processing of the coronavirus MHV-JHM polymerase polyprotein: Identification of precursors and proteolytic products spanning 400 kilodaltons of ORF1a

  👤 Schiller, Jennifer J. 👤 Kanjanahaluethai, Amornrat 👤 Baker, Susan C. ⏰ 1998 📚 Virology

• Activity of a purified His-tagged 3C-like proteinase from the coronavirus infectious bronchitis virus

  👤 Tibbles, K. W. 👤 Cavanagh, D. 👤 Brown, T. D.K. ⏰ 1999 📚 Virus Research

• The N-terminal octapeptide acts as a dimerization inhibitor of SARS coronavirus 3C-like proteinase

  👤 Wei, Ping 👤 Fan, Keqiang 👤 Chen, Hao 👤 Ma, Liang 👤 Huang, Changkang 👤 Tan, Lei 👤 Xi, Dong 👤 Li, Chunmei 👤 Liu, Ying 👤 Cao, Aoneng 👤 Lai, Luhua ⏰ 2006 📚 Biochemical and Biophysical Research Communications

• Further identification and characterization of novel intermediate and mature cleavage products released from the ORF 1b region of the avian coronavirus infectious bronchitis virus 1a/1b polyprotein

  👤 Xu, H. Y. 👤 Lim, K. P. 👤 Shen, S. 👤 Liu, D. X. ⏰ 2001 📚 Virology

• The 3C-like proteinase of an invertebrate nidovirus links coronavirus and potyvirus homologs

  👤 Ziebuhr, John 👤 Bayer, Sonja 👤 Cowley, Jeff A. 👤 Gorbalenya, Alexander E. ⏰ 2003 📚 Journal of Virology