🔗 Antiviral drugs

Articles (60)

• Update on SARS research and other possibly zoonotic coronaviruses

  👤 Anderson, Larry J. 👤 Tong, Suxiang ⏰ 2010 📚 International Journal of Antimicrobial Agents

• Tertiary structure prediction of SARS coronavirus helicase

  👤 Bernini, Andrea 👤 Spiga, Ottavia 👤 Venditti, Vincenzo 👤 Prischi, Filippo 👤 Bracci, Luisa 👤 Huang, Jiandong 👤 Tanner, Julian A. 👤 Niccolai, Neri ⏰ 2006 📚 Biochemical and Biophysical Research Communications

• Coronavirus escape from Heptad Repeat 2 (HR2)-derived peptide entry inhibition as a result of mutations in the HR1 domain of the spike fusion protein

  👤 Bosch, Berend Jan 👤 Rossen, John W.A. 👤 Bartelink, Willem 👤 Zuurveen, Stephanie J. 👤 De Haan, Cornelis A.M. 👤 Duquerroy, Stephane 👤 Boucher, Charles A.B. 👤 Rottier, Peter J.M. ⏰ 2008 📚 Journal of Virology

• The SARS-coronavirus papain-like protease: Structure, function and inhibition by designed antiviral compounds

  👤 Báez-Santos, Yahira M. 👤 St. John, Sarah E. 👤 Mesecar, Andrew D. ⏰ 2015 📚 Antiviral Research

• Recommendations for coronavirus infection in rheumatic diseases treated with biologic therapy.

  👤 Ceribelli, Angela 👤 Motta, Francesca 👤 De Santis, Maria 👤 Ansari, Aftab A 👤 Ridgway, William M 👤 Gershwin, M Eric 👤 Selmi, Carlo ⏰ 2020 📚 J Autoimmun

• Proteolytic processing and deubiquitinating activity of papain-like proteases of human coronavirus NL63

  👤 Chen, Zhongbin 👤 Wang, Yanhua 👤 Ratia, Kiira 👤 Mesecar, Andrew D. 👤 Wilkinson, Keith D. 👤 Baker, Susan C. ⏰ 2007 📚 Journal of Virology

• Thiopurine analogs and mycophenolic acid synergistically inhibit the papain-like protease of Middle East respiratory syndrome coronavirus

  👤 Cheng, Kai Wen 👤 Cheng, Shu Chun 👤 Chen, Wei Yi 👤 Lin, Min Han 👤 Chuang, Shang Ju 👤 Cheng, I. Hsin 👤 Sun, Chiao Yin 👤 Chou, Chi Yuan ⏰ 2015 📚 Antiviral Research

• Molecular advances in severe acute respiratory syndrome-associated coronavirus (SARS-CoV).

  👤 Chow, Ken Yan Ching 👤 Hon, Chung Chau 👤 Hui, Raymond Kin Hi 👤 Wong, Raymond Tsz Yeung 👤 Yip, Chi Wai 👤 Zeng, Fanya 👤 Leung, Frederick Chi Ching ⏰ 2003 📚 Genomics, proteomics & bioinformatics / Beijing Genomics Institute

• A guideline for homology modeling of the proteins from newly discovered betacoronavirus, 2019 novel coronavirus (2019-nCoV).

  👤 Dong, Shengjie 👤 Sun, Jiachen 👤 Mao, Zhuo 👤 Wang, Lu 👤 Lu, Yi-Lin 👤 Li, Jiesen ⏰ 2020 📚 J Med Virol

• Favipiravir: pharmacokinetics and concerns about clinical trials for 2019-nCoV infection.

  👤 Du, Yin-Xiao 👤 Chen, Xiao-Ping ⏰ 2020 📚 Clin Pharmacol Ther

• SKP2 attenuates autophagy through Beclin1-ubiquitination and its inhibition reduces MERS-Coronavirus infection

  👤 Gassen, Nils C. 👤 Niemeyer, Daniela 👤 Muth, Doreen 👤 Corman, Victor M. 👤 Martinelli, Silvia 👤 Gassen, Alwine 👤 Hafner, Kathrin 👤 Papies, Jan 👤 Mösbauer, Kirstin 👤 Zellner, Andreas 👤 Zannas, Anthony S. 👤 Herrmann, Alexander 👤 Holsboer, Florian 👤 Brack-Werner, Ruth 👤 Boshart, Michael 👤 Müller-Myhsok, Bertram 👤 Drosten, Christian 👤 Müller, Marcel A. 👤 Rein, Theo ⏰ 2019 📚 Nature Communications

• A decade after SARS: Strategies for controlling emerging coronaviruses

  👤 Graham, Rachel L. 👤 Donaldson, Eric F. 👤 Baric, Ralph S. ⏰ 2013 📚 Nature Reviews Microbiology

• Interferon-β 1a and SARS Coronavirus Replication

  👤 Hensley, Lisa E. 👤 Fritz, Elizabeth A. 👤 Jahrling, Peter B. 👤 Karp, Christopher L. 👤 Huggins, John W. 👤 Geisbert, Thomas W. ⏰ 2004 📚 Emerging Infectious Diseases

• Generation of synthetic severe acute respiratory syndrome coronavirus pseudoparticles: Implications for assembly and vaccine production

  👤 Huang, Yue 👤 Yang, Zhi Yong 👤 Kong, Wing Pui 👤 Nabel, Gary J. ⏰ 2004 📚 Journal of Virology

• Cardiac Involvement in a Patient With Coronavirus Disease 2019 (COVID-19).

  👤 Inciardi, Riccardo M 👤 Lupi, Laura 👤 Zaccone, Gregorio 👤 Italia, Leonardo 👤 Raffo, Michela 👤 Tomasoni, Daniela 👤 Cani, Dario S 👤 Cerini, Manuel 👤 Farina, Davide 👤 Gavazzi, Emanuele 👤 Maroldi, Roberto 👤 Adamo, Marianna 👤 Ammirati, Enrico 👤 Sinagra, Gianfranco 👤 Lombardi, Carlo M 👤 Metra, Marco ⏰ 2020 📚 JAMA Cardiol

• TMPRSS2 contributes to virus spread and immunopathology in the airways of murine models after coronavirus infection

  👤 Iwata-Yoshikawa, Naoko 👤 Okamura, Tadashi 👤 Shimizu, Yukiko 👤 Hasegawa, Hideki 👤 Takeda, Makoto 👤 Nagata, Noriyo ⏰ 2019 📚 Journal of Virology

• Could Intravenous Immunoglobulin Collected from Recovered Coronavirus Patients Protect against COVID-19 and Strengthen the Immune System of New Patients?

  👤 Jawhara, Samir ⏰ 2020 📚 Int J Mol Sci

• Antiviral activity of chloroquine against human coronavirus OC43 infection in newborn mice

  👤 Keyaerts, Els 👤 Li, Sandra 👤 Vijgen, Leen 👤 Rysman, Evelien 👤 Verbeeck, Jannick 👤 Van Ranst, Marc 👤 Maes, Piet ⏰ 2009 📚 Antimicrobial Agents and Chemotherapy

• Targeting SARS-CoV-2: A Systematic Drug Repurposing Approach to Identify Promising Inhibitors Against 3C-like Proteinase and 2'-O-RiboseMethyltransferase.

  👤 Khan, Rameez Jabeer 👤 Jha, Rajat Kumar 👤 Amera, GizachewMuluneh 👤 Jain, Monika 👤 Singh, Ekampreet 👤 Pathak, Amita 👤 Singh, Rashmi Prabha 👤 Muthukumaran, Jayaraman 👤 Singh, Amit Kumar ⏰ 2020 📚 J Biomol Struct Dyn

• Identification of Chymotrypsin-like Protease Inhibitors of SARS-CoV-2 Via Integrated Computational Approach.

  👤 Khan, Salman Ali 👤 Zia, Komal 👤 Ashraf, Sajda 👤 Uddin, Reaz 👤 Ul-Haq, Zaheer ⏰ 2020 📚 J Biomol Struct Dyn

• Cell-based antiviral screening against coronaviruses: Developing virus-specific and broad-spectrum inhibitors

  👤 Kilianski, Andy 👤 Baker, Susan C. ⏰ 2014 📚 Antiviral Research

• Assessing activity and inhibition of middle east respiratory syndrome coronavirus papain-like and 3C-like proteases using luciferase-based biosensors

  👤 Kilianski, Andy 👤 Mielech, Anna M. 👤 Deng, Xufang 👤 Baker, Susan C. ⏰ 2013 📚 Journal of Virology

• Reversal of the Progression of Fatal Coronavirus Infection in Cats by a Broad-Spectrum Coronavirus Protease Inhibitor

  👤 Kim, Yunjeong 👤 Liu, Hongwei 👤 Galasiti Kankanamalage, Anushka C. 👤 Weerasekara, Sahani 👤 Hua, Duy H. 👤 Groutas, William C. 👤 Chang, Kyeong Ok 👤 Pedersen, Niels C. ⏰ 2016 📚 PLoS Pathogens

• Broad-spectrum inhibitors against 3C-like proteases of feline coronaviruses and feline caliciviruses

  👤 Kim, Yunjeong 👤 Shivanna, Vinay 👤 Narayanan, Sanjeev 👤 Prior, Allan M. 👤 Weerasekara, Sahani 👤 Hua, Duy H. 👤 Galasiti Kankanamalage, Anushka C. 👤 Groutas, William C. 👤 Chang, Kyeong Ok ⏰ 2015 📚 Journal of Virology

• Severe acute respiratory syndrome - A new coronavirus from the Chinese dragon's lair

  👤 Knudsen, T. B. 👤 Kledal, T. N. 👤 Andersen, O. 👤 Eugen-Olsen, J. 👤 Kristiansen, T. B. ⏰ 2003 📚 Scandinavian Journal of Immunology

• Identification and evaluation of potent Middle East respiratory syndrome coronavirus (MERS-CoV) 3CLPro inhibitors

  👤 Kumar, Vathan 👤 Shin, Jin Soo 👤 Shie, Jiun Jie 👤 Ku, Keun Bon 👤 Kim, Chonsaeng 👤 Go, Yun Young 👤 Huang, Kai Fa 👤 Kim, Meehyein 👤 Liang, Po Huang ⏰ 2017 📚 Antiviral Research

• Crystal structure of the papain-like protease of MERS coronavirus reveals unusual, potentially druggable active-site features

  👤 Lei, Jian 👤 Mesters, Jeroen R. 👤 Drosten, Christian 👤 Anemüller, Stefan 👤 Ma, Qingjun 👤 Hilgenfeld, Rolf ⏰ 2014 📚 Antiviral Research

• The epidemic of 2019-novel-coronavirus (2019-nCoV) pneumonia and insights for emerging infectious diseases in the future.

  👤 Li, Jin-Yan 👤 You, Zhi 👤 Wang, Qiong 👤 Zhou, Zhi-Jian 👤 Qiu, Ye 👤 Luo, Rui 👤 Ge, Xing-Yi ⏰ 2020 📚 Microbes Infect

• Structural and functional characterization of MERS coronavirus papain-like protease

  👤 Lin, Min Han 👤 Chuang, Shang Ju 👤 Chen, Chiao Che 👤 Cheng, Shu Chun 👤 Cheng, Kai Wen 👤 Lin, Chao Hsiung 👤 Sun, Chiao Yin 👤 Chou, Chi Yuan ⏰ 2014 📚 Journal of Biomedical Science

• Disulfiram can inhibit MERS and SARS coronavirus papain-like proteases via different modes

  👤 Lin, Min Han 👤 Moses, David C. 👤 Hsieh, Chih Hua 👤 Cheng, Shu Chun 👤 Chen, Yau Hung 👤 Sun, Chiao Yin 👤 Chou, Chi Yuan ⏰ 2018 📚 Antiviral Research

• Pregnancy and Perinatal Outcomes of Women With Coronavirus Disease (COVID-19) Pneumonia: A Preliminary Analysis.

  👤 Liu, Dehan 👤 Li, Lin 👤 Wu, Xin 👤 Zheng, Dandan 👤 Wang, Jiazheng 👤 Yang, Lian 👤 Zheng, Chuansheng ⏰ 2020 📚 AJR Am J Roentgenol

• Drug treatment options for the 2019-new coronavirus (2019-nCoV).

  👤 Lu, Hongzhou ⏰ 2020 📚 Biosci Trends

• Targeting Membrane-Bound Viral RNA Synthesis Reveals Potent Inhibition of Diverse Coronaviruses Including the Middle East Respiratory Syndrome Virus

  👤 Lundin, Anna 👤 Dijkman, Ronald 👤 Bergström, Tomas 👤 Kann, Nina 👤 Adamiak, Beata 👤 Hannoun, Charles 👤 Kindler, Eveline 👤 Jónsdóttir, Hulda R. 👤 Muth, Doreen 👤 Kint, Joeri 👤 Forlenza, Maria 👤 Müller, Marcel A. 👤 Drosten, Christian 👤 Thiel, Volker 👤 Trybala, Edward ⏰ 2014 📚 PLoS Pathogens

• [Management and clinical thinking of Coronavirus Disease 2019].

  👤 Ma, K 👤 Chen, T 👤 Han, M F 👤 Guo, W 👤 Ning, Q ⏰ 2020 📚 Zhonghua Gan Zang Bing Za Zhi

• Clinical characteristics of refractory COVID-19 pneumonia in Wuhan, China.

  👤 Mo, Pingzheng 👤 Xing, Yuanyuan 👤 Xiao, Yu 👤 Deng, Liping 👤 Zhao, Qiu 👤 Wang, Hongling 👤 Xiong, Yong 👤 Cheng, Zhenshun 👤 Gao, Shicheng 👤 Liang, Ke 👤 Luo, Mingqi 👤 Chen, Tielong 👤 Song, Shihui 👤 Ma, Zhiyong 👤 Chen, Xiaoping 👤 Zheng, Ruiying 👤 Cao, Qian 👤 Wang, Fan 👤 Zhang, Yongxi ⏰ 2020 📚 Clin Infect Dis

• Protease inhibitors broadly effective against feline, ferret and mink coronaviruses

  👤 Perera, Krishani Dinali 👤 Galasiti Kankanamalage, Anushka C. 👤 Rathnayake, Athri D. 👤 Honeyfield, Amanda 👤 Groutas, William 👤 Chang, Kyeong Ok 👤 Kim, Yunjeong ⏰ 2018 📚 Antiviral Research

• Inhibition of human coronavirus NL63 infection at early stages of the replication cycle

  👤 Pyrc, Krzysztof 👤 Bosch, Berend Jan 👤 Berkhout, Ben 👤 Jebbink, Maarten F. 👤 Dijkman, Ronald 👤 Rottier, Peter 👤 Van Der Hoek, Lia ⏰ 2006 📚 Antimicrobial Agents and Chemotherapy

• Severe acute respiratory syndrome coronavirus papain-like-protease: Structure of a viral deubiquitinating enzyme

  👤 Ratia, Kiira 👤 Saikatendu, Kumar Singh 👤 Santarsiero, Bernard D. 👤 Barreto, Naina 👤 Baker, Susan C. 👤 Stevens, Raymond C. 👤 Mesecar, Andrew D. ⏰ 2006 📚 Proceedings of the National Academy of Sciences of the United States of America

• [Remdesivir, the antiviral hope against SARS-CoV-2].

  👤 Reina, J ⏰ 2020 📚 Rev Esp Quimioter

• The structure of the endoribonuclease XendoU: From small nucleolar RNA processing to severe acute respiratory syndrome coronavirus replication

  👤 Renzi, Fabiana 👤 Caffarelli, Elisa 👤 Laneve, Pietro 👤 Bozzoni, Irene 👤 Brunori, Maurizio 👤 Vallone, Beatrice ⏰ 2006 📚 Proceedings of the National Academy of Sciences of the United States of America

• Safe and sensitive antiviral screening platform based on recombinant human coronavirus OC43 expressing the luciferase reporter gene

  👤 Shen, Liang 👤 Yang, Yang 👤 Ye, Fei 👤 Liu, Gaoshan 👤 Desforges, Marc 👤 Talbot, Pierre J. 👤 Tan, Wenjie ⏰ 2016 📚 Antimicrobial Agents and Chemotherapy

• COVID-19 infection: Origin, transmission, and characteristics of human coronaviruses.

  👤 Shereen, Muhammad Adnan 👤 Khan, Suliman 👤 Kazmi, Abeer 👤 Bashir, Nadia 👤 Siddique, Rabeea ⏰ 2020 📚 J Adv Res

• The cholesterol transport inhibitor U18666A inhibits type I feline coronavirus infection

  👤 Takano, Tomomi 👤 Endoh, Misaki 👤 Fukatsu, Hiroaki 👤 Sakurada, Haruko 👤 Doki, Tomoyoshi 👤 Hohdatsu, Tsutomu ⏰ 2017 📚 Antiviral Research

• Inhibition of SARS Coronavirus Infection in Vitro with Clinically Approved Antiviral Drugs

  👤 Tan, Emily L.C. 👤 Ooi, Eng Eong 👤 Lin, Chin Yo 👤 Tan, Hwee Cheng 👤 Ling, Ai Ee 👤 Lim, Bing 👤 Stanton, Lawrence W. ⏰ 2004 📚 Emerging Infectious Diseases

• Reverse genetics of SARS-related coronavirus using vaccinia virus-based recombination

  👤 van den Worm, Sjoerd H.E. 👤 Eriksson, Klara Kristin 👤 Zevenhoven, Jessika C. 👤 Weber, Friedemann 👤 Züst, Roland 👤 Kuri, Thomas 👤 Dijkman, Ronald 👤 Chang, Guohui 👤 Siddell, Stuart G. 👤 Snijder, Eric J. 👤 Thiel, Volker 👤 Davidson, Andrew D. ⏰ 2012 📚 PLoS ONE

• Construction of a non-infectious SARS coronavirus replicon for application in drug screening and analysis of viral protein function

  👤 Wang, Jian Min 👤 Wang, Lin Fa 👤 Shi, Zheng Li ⏰ 2008 📚 Biochemical and Biophysical Research Communications

• Antiviral applications of RNAi for coronavirus

  👤 Wu, Chang Jer 👤 Chan, Yi Lin ⏰ 2006 📚 Expert Opinion on Investigational Drugs

• SARS-CoV-2, COVID-19 and inherited arrhythmia syndromes.

  👤 Wu, Cheng-I 👤 Postema, Pieter G 👤 Arbelo, Elena 👤 Behr, Elijah R 👤 Bezzina, Connie R 👤 Napolitano, Carlo 👤 Robyns, Tomas 👤 Probst, Vincent 👤 Schulze-Bahr, Eric 👤 Remme, Carol Ann 👤 Wilde, Arthur A M ⏰ 2020 📚 Heart Rhythm

• Pathological Changes in Masked Palm Civets Experimentally Infected by Severe Acute Respiratory Syndrome (SARS) Coronavirus

  👤 Xiao, Y. 👤 Meng, Q. 👤 Yin, X. 👤 Guan, Y. 👤 Liu, Y. 👤 Li, C. 👤 Wang, M. 👤 Liu, G. 👤 Tong, T. 👤 Wang, L. F. 👤 Kong, X. 👤 Wu, D. ⏰ 2008 📚 Journal of Comparative Pathology

• Molecular model of SARS coronavirus polymerase: Implications for biochemical functions and drug design

  👤 Xu, Xiang 👤 Liu, Yunqing 👤 Weiss, Susan 👤 Arnold, Eddy 👤 Sarafianos, Stefan G. 👤 Ding, Jianping ⏰ 2003 📚 Nucleic Acids Research

• HIV protease inhibitor nelfinavir inhibits replication of SARS-associated coronavirus

  👤 Yamamoto, Norio 👤 Yang, Rongge 👤 Yoshinaka, Yoshiyuki 👤 Amari, Shinji 👤 Nakano, Tatsuya 👤 Cinatl, Jindrich 👤 Rabenau, Holger 👤 Doerr, Hans Wilhelm 👤 Hunsmann, Gerhard 👤 Otaka, Akira 👤 Tamamura, Hirokazu 👤 Fujii, Nobutaka 👤 Yamamoto, Naoki ⏰ 2004 📚 Biochemical and Biophysical Research Communications

• Drug design targeting the main protease, the Achilles' heel of coronaviruses

  👤 Yang, Haitao 👤 Bartlam, Mark 👤 Rao, Zihe ⏰ 2006 📚 Current Pharmaceutical Design

• pH-dependent entry of severe acute respiratory syndrome coronavirus is mediated by the spike glycoprotein and enhanced by dendritic cell transfer through DC-SIGN

  👤 Yang, Zhi Yong 👤 Huang, Yue 👤 Ganesh, Lakshmanan 👤 Leung, Kwanyee 👤 Kong, Wing Pui 👤 Schwartz, Owen 👤 Subbarao, Kanta 👤 Nabel, Gary J. ⏰ 2004 📚 Journal of Virology

• Antiviral effect of lithium chloride and diammonium glycyrrhizinate on porcine deltacoronavirus in vitro

  👤 Zhai, Xiaofeng 👤 Wang, Shilei 👤 Zhu, Mengyan 👤 He, Wei 👤 Pan, Zhongzhou 👤 Su, Shuo ⏰ 2019 📚 Pathogens

• Structural and biochemical characterization of endoribonuclease nsp15 encoded by middle east respiratory syndrome coronavirus

  👤 Zhang, Lianqi 👤 Li, Lei 👤 Yan, Liming 👤 Ming, Zhenhua 👤 Jia, Zhihui 👤 Lou, Zhiyong 👤 Rao, Zihe ⏰ 2018 📚 Journal of Virology

• Clinical trial analysis of 2019-nCoV therapy registered in China.

  👤 Zhang, Qi 👤 Wang, Yakun 👤 Qi, Changsong 👤 Shen, Lin 👤 Li, Jian ⏰ 2020 📚 J Med Virol

• Perspectives on therapeutic neutralizing antibodies against the Novel Coronavirus SARS-CoV-2.

  👤 Zhou, Guangyu 👤 Zhao, Qi ⏰ 2020 📚 Int J Biol Sci

• Identification of novel proteolytically inactive mutations in coronavirus 3C-like protease using a combined approach

  👤 Zhou, Junwei 👤 Fang, Liurong 👤 Yang, Zhixiang 👤 Xu, Shangen 👤 Lv, Mengting 👤 Sun, Zheng 👤 Chen, Jiyao 👤 Wang, Dang 👤 Gao, Jun 👤 Xiao, Shaobo ⏰ 2019 📚 FASEB journal : official publication of the Federation of American Societies for Experimental Biology

• Coronaviruses-drug discovery and therapeutic options

  👤 Zumla, Alimuddin 👤 Chan, Jasper F.W. 👤 Azhar, Esam I. 👤 Hui, David S.C. 👤 Yuen, Kwok Yung ⏰ 2016 📚 Nature Reviews Drug Discovery

• Virulence factors in porcine coronaviruses and vaccine design

  👤 Zuñiga, Sonia 👤 Pascual-Iglesias, Alejandro 👤 Sanchez, Carlos M. 👤 Sola, Isabel 👤 Enjuanes, Luis ⏰ 2016 📚 Virus Research