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Articles (10)
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Crystal structure of the middle east respiratory syndrome coronavirus (MERS-CoV) papain-like protease bound to ubiquitin facilitates targeted disruption of deubiquitinating activity to demonstrate its role in innate immune suppression
π€ Bailey-Elkin, Ben A. π€ Knaap, Robert C.M. π€ Johnson, Garrett G. π€ Dalebout, Tim J. π€ Ninaber, Dennis K. π€ Van Kasteren, Puck B. π€ Bredenbeek, Peter J. π€ Snijder, Eric J. π€ Kikkert, Marjolein π€ Mark, Brian L. β° 2014 π Journal of Biological Chemistry
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X-ray structural and biological evaluation of a series of potent and highly selective inhibitors of human coronavirus papain-like proteases
π€ BΓ‘ez-Santos, Yahira M. π€ Barraza, Scott J. π€ Wilson, Michael W. π€ Agius, Michael P. π€ Mielech, Anna M. π€ Davis, Nicole M. π€ Baker, Susan C. π€ Larsen, Scott D. π€ Mesecar, Andrew D. β° 2014 π Journal of Medicinal Chemistry
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Recognition of Lys48-Linked Di-ubiquitin and Deubiquitinating Activities of the SARS Coronavirus Papain-like Protease
π€ BΓ©kΓ©s, MiklΓ³s π€ van der Heden van Noort, Gerbrand J. π€ Ekkebus, Reggy π€ Ovaa, Huib π€ Huang, Tony T. π€ Lima, Christopher D. β° 2016 π Molecular Cell
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Thiopurine analogue inhibitors of severe acute respiratory syndrome-coronavirus papain-like protease, a deubiquitinating and deISGylating enzyme
π€ Chen, Xin π€ Chou, Chi Yuan π€ Chang, Gu Gang β° 2009 π Antiviral Chemistry and Chemotherapy
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Proteolytic processing and deubiquitinating activity of papain-like proteases of human coronavirus NL63
π€ Chen, Zhongbin π€ Wang, Yanhua π€ Ratia, Kiira π€ Mesecar, Andrew D. π€ Wilkinson, Keith D. π€ Baker, Susan C. β° 2007 π Journal of Virology
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Deubiquitinating and interferon antagonism activities of coronavirus papain-like proteases
π€ Clementz, Mark A. π€ Chen, Zhongbin π€ Banach, Bridget S. π€ Wang, Yanhua π€ Sun, Li π€ Ratia, Kiira π€ Baez-Santos, Yahira M. π€ Wang, Jie π€ Takayama, Jun π€ Ghosh, Arun K. π€ Li, Kui π€ Mesecar, Andrew D. π€ Baker, Susan C. β° 2010 π Journal of Virology
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Structure-Guided Mutagenesis Alters Deubiquitinating Activity and Attenuates Pathogenesis of a Murine Coronavirus.
π€ Deng, Xufang π€ Chen, Yafang π€ Mielech, Anna M π€ Hackbart, Matthew π€ Kesely, Kristina R π€ Mettelman, Robert C π€ O'Brien, Amornrat π€ Chapman, Mackenzie E π€ Mesecar, Andrew D π€ Baker, Susan C β° 2020 π J Virol
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The SARS coronavirus papain like protease can inhibit IRF3 at a post activation step that requires deubiquitination activity
π€ Matthews, Krystal π€ SchΓ€fer, Alexandra π€ Pham, Alissa π€ Frieman, Matthew β° 2014 π Virology Journal
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Coronavirus Endoribonuclease and Deubiquitinating Interferon Antagonists Differentially Modulate the Host Response during Replication in Macrophages.
π€ Volk, Aaron π€ Hackbart, Matthew π€ Deng, Xufang π€ Cruz-Pulido, Yazmin π€ O'Brien, Amornrat π€ Baker, Susan C β° 2020 π J Virol
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Proteolytic processing, deubiquitinase and interferon antagonist activities of Middle East respiratory syndrome coronavirus papain-like protease
π€ Yang, Xingxing π€ Chen, Xiaojuan π€ Bian, Guangxing π€ Tu, Jian π€ Xing, Yaling π€ Wang, Yayun π€ Chen, Zhongbin β° 2014 π Journal of General Virology