π Biochemistry
Articles (54)
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Commentary: Challenges for PhD students during COVID-19 pandemic: Turning crisis into an opportunity.
π€ Aydemir, Duygu π€ Ulusu, Nuriye N β° 2020 π Biochem Mol Biol Educ
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Crystal structure of the middle east respiratory syndrome coronavirus (MERS-CoV) papain-like protease bound to ubiquitin facilitates targeted disruption of deubiquitinating activity to demonstrate its role in innate immune suppression
π€ Bailey-Elkin, Ben A. π€ Knaap, Robert C.M. π€ Johnson, Garrett G. π€ Dalebout, Tim J. π€ Ninaber, Dennis K. π€ Van Kasteren, Puck B. π€ Bredenbeek, Peter J. π€ Snijder, Eric J. π€ Kikkert, Marjolein π€ Mark, Brian L. β° 2014 π Journal of Biological Chemistry
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Elastase-mediated activation of the severe acute respiratory syndrome coronavirus spike protein at discrete sites within the S2 domain
π€ Belouzard, Sandrine π€ Madu, Ikenna π€ Whittaker, Gary R. β° 2010 π Journal of Biological Chemistry
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Structural and functional analyses of the severe acute respiratory syndrome coronavirus endoribonuclease Nsp15
π€ Bhardwaj, Kanchan π€ Palaninathan, Satheesh π€ Alcantara, Joanna Maria Ortiz π€ Yi, Lillian Li π€ Guarino, Linda π€ Sacchettini, James C. π€ Kao, C. Cheng β° 2008 π Journal of Biological Chemistry
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Coronavirus Nsp10, a critical co-factor for activation of multiple replicative enzymes
π€ Bouvet, MickaΓ«l π€ Lugari, Adrien π€ Posthuma, Clara C. π€ Zevenhoven, Jessika C. π€ Bernard, StΓ©phanie π€ Betzi, StΓ©phane π€ Imbert, Isabelle π€ Canard, Bruno π€ Guillemot, Jean Claude π€ LΓ©cine, Patrick π€ Pfefferle, Susanne π€ Drosten, Christian π€ Snijder, Eric J. π€ Decroly, Etienne π€ Morelli, Xavier β° 2014 π Journal of Biological Chemistry
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Mutation of Gly-11 on the dimer interface results in the complete crystallographic dimer dissociation of severe acute respiratory syndrome coronavirus 3C-like protease: Crystal structure with molecular dynamics simulations
π€ Chen, Shuai π€ Hu, Tiancen π€ Zhang, Jian π€ Chen, Jing π€ Chen, Kaixian π€ Ding, Jianping π€ Jiang, Hualiang π€ Shen, Xu β° 2008 π Journal of Biological Chemistry
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Macro domain from middle east respiratory syndrome coronavirus (MERS-CoV) is an efficient ADP-ribose binding module: Crystal structure and biochemical studies
π€ Cho, Chao Cheng π€ Lin, Meng Hsuan π€ Chuang, Chien Ying π€ Hsu, Chun Hua β° 2016 π Journal of Biological Chemistry
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GxxxG motif of severe acute respiratory syndrome coronavirus spike glycoprotein transmembrane domain is not involved in trimerization and is not important for entry
π€ Corver, Jeroen π€ Broer, Rene π€ Van Kasteren, Puck π€ Spaan, Willy β° 2007 π Journal of Virology
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Regulation of IRF-3-dependent innate immunity by the papain-like protease domain of the severe acute respiratory syndrome coronavirus
π€ Devaraj, Santhana G. π€ Wang, Nan π€ Chen, Zhongbin π€ Chen, Zihong π€ Tseng, Monica π€ Barretto, Naina π€ Lin, Rongtuan π€ Peters, Clarence J. π€ Tseng, Chien Te K. π€ Baker, Susan C. π€ Li, Kui β° 2007 π Journal of Biological Chemistry
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Inhibitor design for SARS coronavirus main protease based on "distorted key theory"
π€ Du, Qi Shi π€ Sun, Hao π€ Chou, Kuo Chen β° 2007 π Medicinal Chemistry
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Quantitative proteomics using stable isotope labeling with amino acids in cell culture reveals changes in the cytoplasmic, nuclear, and nucleolar proteomes in vero cells infected with the coronavirus infectious bronchitis virus
π€ Emmott, Edward π€ Rodgers, Mark A. π€ Macdonald, Andrew π€ McCrory, Sarah π€ Ajuh, Paul π€ Hiscox, Julian A. β° 2010 π Molecular and Cellular Proteomics
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Solution structure of the severe acute respiratory syndrome-coronavirus heptad repeat 2 domain in the prefusion state
π€ Hakansson-McReynolds, Susanna π€ Jiang, Shaokai π€ Rong, Lijun π€ Caffrey, Michael β° 2006 π Journal of Biological Chemistry
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Critical assessment of important regions in the subunit association and catalytic action of the severe acute respiratory syndrome coronavirus main protease
π€ Hsu, Wen Chi π€ Chang, Hui Chuan π€ Chou, Chi Yuan π€ Tsai, Pui Jen π€ Lin, Pei In π€ Chang, Gu Gang β° 2005 π Journal of Biological Chemistry
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SARS coronavirus, but not human coronavirus NL63, utilizes cathepsin L to infect ACE2-expressing cells
π€ Huang, I. Chueh π€ Bosch, Berend Jan π€ Li, Fang π€ Li, Wenhui π€ Kyoung, Hoa Lee π€ Ghiran, Sorina π€ Vasilieva, Natalya π€ Dermody, Terence S. π€ Harrison, Stephen C. π€ Dormitzer, Philip R. π€ Farzan, Michael π€ Rottier, Peter J.M. π€ Choe, Hyeryun β° 2006 π Journal of Biological Chemistry
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Quantitative analysis of Severe Acute Respiratory Syndrome (SARS)-associated coronavirus-infected cells using proteomic approaches: Implications for cellular responses to virus infection
π€ Jiang, Xiao Sheng π€ Tang, Liu Ya π€ Dai, Jie π€ Zhou, Hu π€ Li, Su Jun π€ Xia, Qi Chang π€ Wu, Jia Rui π€ Zeng, Rong β° 2005 π Molecular and Cellular Proteomics
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A Comprehensive Literature Review on the Clinical Presentation, and Management of the Pandemic Coronavirus Disease 2019 (COVID-19).
π€ Kakodkar, Pramath π€ Kaka, Nagham π€ Baig, M N β° 2020 π Cureus
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Tumor necrosis factor-Ξ± convertase (ADAM17) mediates regulated ectodomain shedding of the severe-acute respiratory syndrome-coronavirus (SARS-CoV) receptor, angiotensin-converting enzyme-2 (ACE2)
π€ Lambert, Daniel W. π€ Yarski, Mike π€ Warner, Fiona J. π€ Thornhill, Paul π€ Parkin, Edward T. π€ Smith, A. Ian π€ Hooper, Nigel M. π€ Turner, Anthony J. β° 2005 π Journal of Biological Chemistry
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Maturation mechanism of severe acute respiratory syndrome (SARS) coronavirus 3C-like proteinase
π€ Li, Chunmei π€ Qi, Yifei π€ Teng, Xin π€ Yang, Zongchang π€ Wei, Ping π€ Zhang, Changsheng π€ Tan, Lei π€ Zhou, Lu π€ Liu, Ying π€ Lai, Luhua β° 2010 π Journal of Biological Chemistry
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Structure of a conserved golgi complex-targeting signal in coronavirus envelope proteins
π€ Li, Yan π€ Surya, Wahyu π€ Claudine, Stephanie π€ Torres, Jaume β° 2014 π Journal of Biological Chemistry
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mRNA display design of fibronectin-based intrabodies that detect and inhibit severe acute respiratory syndrome coronavirus nucleocapsid protein
π€ Liao, Hsiang I. π€ Olson, C. Anders π€ Hwang, Seungmin π€ Deng, Hongyu π€ Wong, Elaine π€ Baric, Ralph S. π€ Roberts, Richard W. π€ Sun, Ren β° 2009 π Journal of Biological Chemistry
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Activation of NF-ΞΊB by the full-length nucleocapsid protein of the SARS coronavirus
π€ Liao, Qing Jiao π€ Ye, Lin Bai π€ Timani, Khalid Amine π€ Zeng, Ying Chun π€ She, Ying Long π€ Ye, Li π€ Wu, Zheng Hui β° 2005 π Acta Biochimica et Biophysica Sinica
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Pyogranulomatous panophthalmitis with systemic coronavirus disease in a domestic ferret (Mustela putorius furo)
π€ Lindemann, Dana M. π€ Eshar, David π€ Schumacher, Loni L. π€ Almes, Kelli M. π€ Rankin, Amy J. β° 2016 π Veterinary Ophthalmology
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Cell entry of porcine epidemic diarrhea coronavirus is activated by lysosomal proteases
π€ Liu, Chang π€ Ma, Yuanmei π€ Yang, Yang π€ Zheng, Yuan π€ Shang, Jian π€ Zhou, Yusen π€ Jiang, Shibo π€ Du, Lanying π€ Li, Jianrong π€ Li, Fang β° 2016 π Journal of Biological Chemistry
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Clinical and biochemical indexes from 2019-nCoV infected patients linked to viral loads and lung injury.
π€ Liu, Yingxia π€ Yang, Yang π€ Zhang, Cong π€ Huang, Fengming π€ Wang, Fuxiang π€ Yuan, Jing π€ Wang, Zhaoqin π€ Li, Jinxiu π€ Li, Jianming π€ Feng, Cheng π€ Zhang, Zheng π€ Wang, Lifei π€ Peng, Ling π€ Chen, Li π€ Qin, Yuhao π€ Zhao, Dandan π€ Tan, Shuguang π€ Yin, Lu π€ Xu, Jun π€ Zhou, Congzhao π€ Jiang, Chengyu π€ Liu, Lei β° 2020 π Sci China Life Sci
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Sequence analysis and structural prediction of the severe acute respiratory syndrome coronavirus nsp5
π€ Lu, Jia Hai π€ Zhang, Ding Mei π€ Wang, Guo Ling π€ Guo, Zhong Min π€ Li, Juan π€ Tan, Bing Yan π€ Ou-Yang, Li Ping π€ Ling, Wen Hua π€ Yu, Xin Bing π€ Zhong, Nan Shan β° 2005 π Acta Biochimica et Biophysica Sinica
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Molecular mapping of the RNA cap 2β²-O-methyltransferase activation interface between severe acute respiratory syndrome coronavirus nsp10 and nsp16
π€ Lugari, Adrien π€ Betzi, Stephane π€ Decroly, Etienne π€ Bonnaud, Emmanuel π€ Hermant, AurΓ©lie π€ Guillemot, Jean Claude π€ Debarnot, Claire π€ Borg, Jean Paul π€ Bouvet, MickaΓ«l π€ Canard, Bruno π€ Morelli, Xavier π€ LΓ©cine, Patrick β° 2010 π Journal of Biological Chemistry
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Disease features of equine coronavirus and enteric salmonellosis are similar in horses
π€ Manship, Arlie J. π€ Blikslager, Anthony T. π€ Elfenbein, Johanna R. β° 2019 π Journal of Veterinary Internal Medicine
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Glycosylation of the viral attachment protein of avian coronavirus is essential for host cell and receptor binding
π€ Parsons, Lisa M. π€ Bouwman, Kim M. π€ Azurmendi, Hugo π€ De Vries, Robert P. π€ Cipollo, John F. π€ Verheije, Monique H. β° 2019 π Journal of Biological Chemistry
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Crystal structure of bovine coronavirus spike protein lectin domain
π€ Peng, Guiqing π€ Xu, Liqing π€ Lin, Yi Lun π€ Chen, Lang π€ Pasquarella, Joseph R. π€ Holmes, Kathryn V. π€ Li, Fang β° 2012 π Journal of Biological Chemistry
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Structural and molecular evidence suggesting coronavirus-driven evolution of mouse receptor
π€ Peng, Guiqing π€ Yang, Yang π€ Pasquarella, Joseph R. π€ Xu, Liqing π€ Qian, Zhaohui π€ Holmes, Kathryn V. π€ Li, Fang β° 2017 π Journal of Biological Chemistry
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The C-terminal domain of the MERS coronavirusMprotein contains a trans-Golgi network localization signal
π€ Perrier, Anabelle π€ Bonnin, Ariane π€ Desmarets, Lowiese π€ Danneels, Adeline π€ Goffard, Anne π€ RouillΓ©, Yves π€ Dubuisson, Jean π€ Belouzard, Sandrine β° 2019 π Journal of Biological Chemistry
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Culturing the unculturable: Human coronavirus HKU1 infects, replicates, and produces progeny virions in human ciliated airway epithelial cell cultures
π€ Pyrc, Krzysztof π€ Sims, Amy C. π€ Dijkman, Ronald π€ Jebbink, Maarten π€ Long, Casey π€ Deming, Damon π€ Donaldson, Eric π€ Vabret, Astrid π€ Baric, Ralph π€ Van Der Hoek, Lia π€ Pickles, Raymond β° 2010 π Journal of Virology
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Identification of two critical amino acid residues of the severe acute respiratory syndrome coronavirus spike protein for its variation in zoonotic tropism transition via a double substitution strategy
π€ Qu, Xiu Xia π€ Hao, Pei π€ Song, Xi Jun π€ Jiang, Si Ming π€ Liu, Yan Xia π€ Wang, Pei Gang π€ Rao, Xi π€ Song, Huai Dong π€ Wang, Sheng Yue π€ Zuo, Yu π€ Zheng, Ai Hua π€ Luo, Min π€ Wang, Hua Lin π€ Deng, Fei π€ Wang, Han Zhong π€ Hu, Zhi Hong π€ Ding, Ming Xiao π€ Zhao, Guo Ping π€ Deng, Hong Kui β° 2005 π Journal of Biological Chemistry
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Insights into RNA synthesis, capping, and proofreading mechanisms of SARS-coronavirus
π€ Sevajol, Marion π€ Subissi, Lorenzo π€ Decroly, Etienne π€ Canard, Bruno π€ Imbert, Isabelle β° 2014 π Virus Research
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Study on substrate specificity at sub sites for severe acute respiratory syndrome coronavirus 3CL protease
π€ Shan, Yu Fei π€ Xu, Gen Jun β° 2005 π Acta Biochimica et Biophysica Sinica
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A conserved region of nonstructural protein 1 from alphacoronaviruses inhibits host gene expression and is critical for viral virulence
π€ Shen, Zhou π€ Wang, Gang π€ Yang, Yiling π€ Shi, Jiale π€ Fang, Liurong π€ Li, Fang π€ Xiao, Shaobo π€ Fu, Zhen F. π€ Peng, Guiqing β° 2019 π Journal of Biological Chemistry
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Role of spike protein endodomains in regulating coronavirus entry
π€ Shulla, Ana π€ Gallagher, Tom β° 2009 π Journal of Biological Chemistry
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Severe acute respiratory syndrome coronavirus M protein inhibits type I interferon production by impeding theformation of TRAF3Β·TANKΒ·TBK1/IKKΞ΅ complex
π€ Siu, Kam Leung π€ Kok, Kin Hang π€ Ng, Ming Him James π€ Poon, Vincent K.M. π€ Yuen, Kwok Yung π€ Zheng, Bo Jian π€ Jin, Dong Yan β° 2009 π Journal of Biological Chemistry
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Nidovirus sialate-O-acetylesterases: Evolution and substrate specificity of coronaviral and toroviral receptor-destroying enzymes
π€ Smits, Saskia L. π€ Gerwig, Gerrit J. π€ Van Vliet, Arno L.W. π€ Lissenberg, Arjen π€ Briza, Peter π€ Kamerling, Johannis P. π€ Vlasak, Reinhard π€ De Groot, Raoul J. β° 2005 π Journal of Biological Chemistry
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The nucleocapsid protein of severe acute respiratory syndrome-coronavirus inhibits the activity of cyclin-cyclin-dependent kinase complex and blocks S phase progression in mammalian cells
π€ Surjit, Milan π€ Liu, Boping π€ Chow, Vincent T.K. π€ Lal, Sunil K. β° 2006 π Journal of Biological Chemistry
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Ligand-induced dimerization of Middle East Respiratory Syndrome (MERS) Coronavirus nsp5 protease (3CLpro): Implications for nsp5 regulation and the development of antivirals
π€ Tomar, Sakshi π€ Johnston, Melanie L. π€ John, Sarah E.St π€ Osswald, Heather L. π€ Nyalapatla, Prasanth R. π€ Paul, Lake N. π€ Ghosh, Arun K. π€ Denison, Mark R. π€ Mesecar, Andrew D. β° 2015 π Journal of Biological Chemistry
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Self-assembly of severe acute respiratory syndrome coronavirus membrane protein
π€ Tseng, Ying Tzu π€ Wang, Shiu Mei π€ Huang, Kuo Jung π€ I-Ru Lee, Amber π€ Chiang, Chien Cheng π€ Wang, Chin Tien β° 2010 π Journal of Biological Chemistry
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Glycogen synthase kinase-3 regulates the phosphorylation of severe acute respiratory syndrome coronavirus mucleocapsid protein and viral replication
π€ Wu, Chia Hsin π€ Yeh, Shiou Hwei π€ Tsay, Yeou Guang π€ Shieh, Ya Hsiung π€ Kao, Chuan Liang π€ Chen, Yen Shun π€ Wang, Sheng Han π€ Kuo, Ti Jung π€ Chen, Ding Shinn π€ Chen, Pei Jer β° 2009 π Journal of Biological Chemistry
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Mechanisms of host receptor adaptation by severe acute respiratory syndrome coronavirus
π€ Wu, Kailang π€ Peng, Guiqing π€ Wilken, Matthew π€ Geraghty, Robert J. π€ Li, Fang β° 2012 π Journal of Biological Chemistry
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Coronavirus infection induces DNA replication stress partly through interaction of its nonstructural protein 13 with the p125 subunit of DNA polymerase Ξ΄
π€ Xu, Ling Hui π€ Huang, Mei π€ Fang, Shou Guo π€ Liu, Ding Xiang β° 2011 π Journal of Biological Chemistry
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Phosphatidylinositol 4-kinase IIIΞ² is required for severe acute respiratory syndrome coronavirus spike-mediated cell entry
π€ Yang, Ning π€ Ping, Ma π€ Lang, Jianshe π€ Zhang, Yanli π€ Deng, Jiejie π€ Ju, Xiangwu π€ Zhang, Gongyi π€ Jiang, Chengyu β° 2012 π Journal of Biological Chemistry
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Clinical efficacy of lopinavir/ritonavir in the treatment of Coronavirus disease 2019.
π€ Ye, X-T π€ Luo, Y-L π€ Xia, S-C π€ Sun, Q-F π€ Ding, J-G π€ Zhou, Y π€ Chen, W π€ Wang, X-F π€ Zhang, W-W π€ Du, W-J π€ Ruan, Z-W π€ Hong, L β° 2020 π Eur Rev Med Pharmacol Sci
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Recombinant severe acute respiratory syndrome (SARS) coronavirus nucleocapsid protein forms a dimer through its C-terminal domain
π€ Yu, I. Mei π€ Gustafson, Christin L.T. π€ Diao, Jianbo π€ Burgner II, John W. π€ Li, Zhihong π€ Zhang, Jingqiang π€ Chen, Jue β° 2005 π Journal of Biological Chemistry
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Crystal structure of the severe acute respiratory syndrome (SARS) coronavirus nucleocapsid protein dimerization domain reveals evolutionary linkage between Corona- and Arteriviridae
π€ Yu, I. Mei π€ Oldham, Michael L. π€ Zhang, Jingqiang π€ Chen, Jue β° 2006 π Journal of Biological Chemistry
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P53 degradation by a coronavirus papain-like protease suppresses type I interferon signaling
π€ Yuan, Lin π€ Chen, Zhongbin π€ Song, Shanshan π€ Wang, Shan π€ Tian, Chunyan π€ Xing, Guichun π€ Chen, Xiaojuan π€ Xiao, Zhi Xiong π€ He, Fuchu π€ Zhang, Lingqiang β° 2015 π Journal of Biological Chemistry
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Porcine deltacoronavirus enters cells via two pathways: A protease-mediated one at the cell surface and another facilitated by cathepsins in the endosome
π€ Zhang, Jialin π€ Chen, Jianfei π€ Shi, Da π€ Shi, Hongyan π€ Zhang, Xin π€ Liu, Jianbo π€ Cao, Liyan π€ Zhu, Xiangdong π€ Liu, Ye π€ Wang, Xiaobo π€ Ji, Zhaoyang π€ Feng, Li β° 2019 π Journal of Biological Chemistry
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Severe acute respiratory syndrome-associated coronavirus nucleocapsid protein interacts with Smad3 and modulates transforming growth factor-Ξ² signaling
π€ Zhao, Xingang π€ Nicholls, John M. π€ Chen, Ye Guang β° 2008 π Journal of Biological Chemistry
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Insight into the evolution of nidovirus endoribonuclease based on the finding that nsp15 from porcine Deltacoronavirus functions as a dimer
π€ Zheng, Anjun π€ Shi, Yuejun π€ Shen, Zhou π€ Wang, Gang π€ Shi, Jiale π€ Xiong, Qiqi π€ Fang, Liurong π€ Xiao, Shaobo π€ Fu, Zhen F. π€ Peng, Guiqing β° 2018 π Journal of Biological Chemistry
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Glycopeptide antibiotics potently inhibit cathepsin l in the late endosome/lysosome and block the entry of ebola virus, middle east respiratory syndrome coronavirus (MERS-CoV), and severe acute respiratory syndrome coronavirus (SARS-CoV)
π€ Zhou, Nan π€ Pan, Ting π€ Zhang, Junsong π€ Li, Qianwen π€ Zhang, Xue π€ Bai, Chuan π€ Huang, Feng π€ Peng, Tao π€ Zhang, Jianhua π€ Liu, Chao π€ Tao, Liang π€ Zhang, Hui β° 2016 π Journal of Biological Chemistry