🔗 Protease inhibitors

Articles (27)

• A chimeric virus-mouse model system for evaluating the function and inhibition of papain-like proteases of emerging coronaviruses

  👤 Deng, Xufang 👤 Agnihothram, Sudhakar 👤 Mielech, Anna M. 👤 Nichols, Daniel B. 👤 Wilson, Michael W. 👤 St. John, Sarah E. 👤 Larsen, Scott D. 👤 Mesecar, Andrew D. 👤 Lenschow, Deborah J. 👤 Baric, Ralph S. 👤 Baker, Susan C. ⏰ 2014 📚 Journal of Virology

• Coronaviruses resistant to a 3C-like protease inhibitor are attenuated for replication and pathogenesis, revealing a low genetic barrier but high fitness cost of resistance

  👤 Deng, Xufang 👤 St John, Sarah E. 👤 Osswald, Heather L. 👤 O'Brien, Amornrat 👤 Banach, Bridget S. 👤 Sleeman, Katrina 👤 Ghosh, Arun K. 👤 Mesecar, Andrew D. 👤 Baker, Susan C. ⏰ 2014 📚 Journal of Virology

• Identifying inhibitors of the SARS coronavirus proteinase

  👤 Jenwitheesuk, Ekachai 👤 Samudrala, Ram ⏰ 2003 📚 Bioorganic and Medicinal Chemistry Letters

• Protease-mediated entry via the endosome of human coronavirus 229E

  👤 Kawase, Miyuki 👤 Shirato, Kazuya 👤 Matsuyama, Shutoku 👤 Taguchi, Fumihiro ⏰ 2009 📚 Journal of Virology

• Identification of Chymotrypsin-like Protease Inhibitors of SARS-CoV-2 Via Integrated Computational Approach.

  👤 Khan, Salman Ali 👤 Zia, Komal 👤 Ashraf, Sajda 👤 Uddin, Reaz 👤 Ul-Haq, Zaheer ⏰ 2020 📚 J Biomol Struct Dyn

• Assessing activity and inhibition of middle east respiratory syndrome coronavirus papain-like and 3C-like proteases using luciferase-based biosensors

  👤 Kilianski, Andy 👤 Mielech, Anna M. 👤 Deng, Xufang 👤 Baker, Susan C. ⏰ 2013 📚 Journal of Virology

• Broad-spectrum antivirals against 3C or 3C-like proteases of picornaviruses, noroviruses, and coronaviruses

  👤 Kim, Yunjeong 👤 Lovell, Scott 👤 Tiew, Kok Chuan 👤 Mandadapu, Sivakoteswara Rao 👤 Alliston, Kevin R. 👤 Battaile, Kevin K. 👤 Groutas, William C. 👤 Chang, Kyeong Ok ⏰ 2012 📚 Journal of Virology

• Potent inhibition of feline coronaviruses with peptidyl compounds targeting coronavirus 3C-like protease

  👤 Kim, Yunjeong 👤 Mandadapu, Sivakoteswara Rao 👤 Groutas, William C. 👤 Chang, Kyeong Ok ⏰ 2013 📚 Antiviral Research

• Mutational and inhibitive analysis of SARS coronavirus 3C-like protease by fluorescence resonance energy transfer-based assays

  👤 Kuang, Wan Fen 👤 Chow, Lu Ping 👤 Wu, Mei Hua 👤 Hwang, Lih Hwa ⏰ 2005 📚 Biochemical and Biophysical Research Communications

• Individual and common inhibitors of coronavirus and picornavirus main proteases

  👤 Kuo, Chih Jung 👤 Liu, Hun Ge 👤 Lo, Yueh Kuei 👤 Seong, Churl Min 👤 Lee, Kee In 👤 Jung, Young Sik 👤 Liang, Po Huang ⏰ 2009 📚 FEBS Letters

• Compounds with therapeutic potential against novel respiratory 2019 coronavirus.

  👤 Martinez, Miguel Angel ⏰ 2020 📚 Antimicrob Agents Chemother

• Middle east respiratory syndrome coronavirus spike protein is not activated directly by cellular furin during viral entry into target cells

  👤 Matsuyama, Shutoku 👤 Shirato, Kazuya 👤 Kawase, Miyuki 👤 Terada, Yutaka 👤 Kawachi, Kengo 👤 Fukushi, Shuetsu 👤 Kamitani, Wataru ⏰ 2018 📚 Journal of Virology

• Macrolide treatment for COVID-19: Will this be the way forward?

  👤 Ohe, Masashi 👤 Shida, Haruki 👤 Jodo, Satoshi 👤 Kusunoki, Yoshihiro 👤 Seki, Masahide 👤 Furuya, Ken 👤 Goudarzi, Houman ⏰ 2020 📚 Biosci Trends

• Unrevealing sequence and structural features of novel coronavirus using in silico approaches: The main protease as molecular target.

  👤 Ortega, Joseph Thomas 👤 Serrano, Maria Luisa 👤 Pujol, Flor Helene 👤 Rangel, Hector Rafael ⏰ 2020 📚 EXCLI J

• Protease inhibitors broadly effective against feline, ferret and mink coronaviruses

  👤 Perera, Krishani Dinali 👤 Galasiti Kankanamalage, Anushka C. 👤 Rathnayake, Athri D. 👤 Honeyfield, Amanda 👤 Groutas, William 👤 Chang, Kyeong Ok 👤 Kim, Yunjeong ⏰ 2018 📚 Antiviral Research

• Characterization of amino acid substitutions in feline coronavirus 3C-like protease from a cat with feline infectious peritonitis treated with a protease inhibitor

  👤 Perera, Krishani Dinali 👤 Rathnayake, Athri 👤 Liu, Hongwei 👤 Pedersen, Niels C. 👤 Groutas, William C. 👤 Chang, Kyeong Ok 👤 Kim, Yunjeong ⏰ 2019 📚 Veterinary Microbiology

• Synthesis and evaluation of pyrazolone compounds as SARS-coronavirus 3C-like protease inhibitors

  👤 Ramajayam, R. 👤 Tan, Kian Pin 👤 Liu, Hun Ge 👤 Liang, Po Huang ⏰ 2010 📚 Bioorganic and Medicinal Chemistry

• Potential therapies for coronaviruses

  👤 Savarino, Andrea 👤 Bounavoglia, Canio 👤 Norelli, Sandro 👤 Di Trani, Livia 👤 Cassone, Antonio ⏰ 2006 📚 Expert Opinion on Therapeutic Patents

• Clinical isolates of human coronavirus 229E bypass the endosome for cell entry

  👤 Shirato, Kazuya 👤 Kanou, Kazuhiko 👤 Kawase, Miyuki 👤 Matsuyama, Shutoku ⏰ 2017 📚 Journal of Virology

• Inhibition of SARS Coronavirus Infection in Vitro with Clinically Approved Antiviral Drugs

  👤 Tan, Emily L.C. 👤 Ooi, Eng Eong 👤 Lin, Chin Yo 👤 Tan, Hwee Cheng 👤 Ling, Ai Ee 👤 Lim, Bing 👤 Stanton, Lawrence W. ⏰ 2004 📚 Emerging Infectious Diseases

• SARS coronavirus anti-infectives.

  👤 Tong, Tommy R. ⏰ 2006 📚 Recent patents on anti-infective drug discovery

• Therapies for coronaviruses. Part 2: Inhibitors of intracellular life cycle

  👤 Tong, Tommy R. ⏰ 2009 📚 Expert Opinion on Therapeutic Patents

• The management of coronavirus infections with particular reference to SARS

  👤 Wong, Samson S.Y. 👤 Yuen, Kwok Yung ⏰ 2008 📚 Journal of Antimicrobial Chemotherapy

• Synthesis, crystal structure, structure-activity relationships, and antiviral activity of a potent SARS coronavirus 3CL protease inhibitor

  👤 Yang, Syaulan 👤 Chen, Shu Jen 👤 Hsu, Min Feng 👤 Wu, Jen Dar 👤 Tseng, Chien Te K. 👤 Liu, Yu Fan 👤 Chen, Hua Chien 👤 Kuo, Chun Wei 👤 Wu, Chi Shen 👤 Chang, Li Wen 👤 Chen, Wen Chang 👤 Liao, Shao Ying 👤 Chang, Teng Yuan 👤 Hung, Hsin Hui 👤 Shr, Hui Lin 👤 Liu, Cheng Yuan 👤 Huang, Yu An 👤 Chang, Ling Yin 👤 Hsu, Jen Chi 👤 Peters, Clarence J. 👤 Wang, Andrew H.J. 👤 Hsu, Ming Chu ⏰ 2006 📚 Journal of Medicinal Chemistry

• Identification of novel proteolytically inactive mutations in coronavirus 3C-like protease using a combined approach

  👤 Zhou, Junwei 👤 Fang, Liurong 👤 Yang, Zhixiang 👤 Xu, Shangen 👤 Lv, Mengting 👤 Sun, Zheng 👤 Chen, Jiyao 👤 Wang, Dang 👤 Gao, Jun 👤 Xiao, Shaobo ⏰ 2019 📚 FASEB journal : official publication of the Federation of American Societies for Experimental Biology

• Protease inhibitors targeting coronavirus and filovirus entry

  👤 Zhou, Yanchen 👤 Vedantham, Punitha 👤 Lu, Kai 👤 Agudelo, Juliet 👤 Carrion, Ricardo 👤 Nunneley, Jerritt W. 👤 Barnard, Dale 👤 Pöhlmann, Stefan 👤 McKerrow, James H. 👤 Renslo, Adam R. 👤 Simmons, Graham ⏰ 2015 📚 Antiviral Research

• TMPRSS11A activates the influenza A virus hemagglutinin and the MERS coronavirus spike protein and is insensitive against blockade by HAI-1

  👤 Zmora, Pawel 👤 Hoffmann, Markus 👤 Kollmus, Heike 👤 Moldenhauer, Anna Sophie 👤 Danov, Olga 👤 Braun, Armin 👤 Winkler, Michael 👤 Schughart, Klaus 👤 Stefan Pöhlmann, X. ⏰ 2018 📚 Journal of Biological Chemistry