🔗 Viral replicase

Articles (18)

• Construction of a severe acute respiratory syndrome coronavirus infectious cDNA clone and a replicon to study coronavirus RNA synthesis

  👤 Almazán, Fernando 👤 DeDiego, Marta L. 👤 Galán, Carmen 👤 Escors, David 👤 Álvarez, Enrique 👤 Ortego, Javier 👤 Sola, Isabel 👤 Zuñiga, Sonia 👤 Alonso, Sara 👤 Moreno, Jose L. 👤 Nogales, Aitor 👤 Capiscol, Carmen 👤 Enjuanes, Luis ⏰ 2006 📚 Journal of Virology

• Novel β-barrel fold in the nuclear magnetic resonance structure of the replicase nonstructural protein 1 from the severe acute respiratory syndrome coronavirus

  👤 Almeida, Marcius S. 👤 Johnson, Margaret A. 👤 Herrmann, Torsten 👤 Geralt, Michael 👤 Wüthrich, Kurt ⏰ 2007 📚 Journal of Virology

• Crystal structure of the middle east respiratory syndrome coronavirus (MERS-CoV) papain-like protease bound to ubiquitin facilitates targeted disruption of deubiquitinating activity to demonstrate its role in innate immune suppression

  👤 Bailey-Elkin, Ben A. 👤 Knaap, Robert C.M. 👤 Johnson, Garrett G. 👤 Dalebout, Tim J. 👤 Ninaber, Dennis K. 👤 Van Kasteren, Puck B. 👤 Bredenbeek, Peter J. 👤 Snijder, Eric J. 👤 Kikkert, Marjolein 👤 Mark, Brian L. ⏰ 2014 📚 Journal of Biological Chemistry

• Proteolytic processing and deubiquitinating activity of papain-like proteases of human coronavirus NL63

  👤 Chen, Zhongbin 👤 Wang, Yanhua 👤 Ratia, Kiira 👤 Mesecar, Andrew D. 👤 Wilkinson, Keith D. 👤 Baker, Susan C. ⏰ 2007 📚 Journal of Virology

• Deubiquitinating and interferon antagonism activities of coronavirus papain-like proteases

  👤 Clementz, Mark A. 👤 Chen, Zhongbin 👤 Banach, Bridget S. 👤 Wang, Yanhua 👤 Sun, Li 👤 Ratia, Kiira 👤 Baez-Santos, Yahira M. 👤 Wang, Jie 👤 Takayama, Jun 👤 Ghosh, Arun K. 👤 Li, Kui 👤 Mesecar, Andrew D. 👤 Baker, Susan C. ⏰ 2010 📚 Journal of Virology

• Structure-Guided Mutagenesis Alters Deubiquitinating Activity and Attenuates Pathogenesis of a Murine Coronavirus.

  👤 Deng, Xufang 👤 Chen, Yafang 👤 Mielech, Anna M 👤 Hackbart, Matthew 👤 Kesely, Kristina R 👤 Mettelman, Robert C 👤 O'Brien, Amornrat 👤 Chapman, Mackenzie E 👤 Mesecar, Andrew D 👤 Baker, Susan C ⏰ 2020 📚 J Virol

• Coronaviruses resistant to a 3C-like protease inhibitor are attenuated for replication and pathogenesis, revealing a low genetic barrier but high fitness cost of resistance

  👤 Deng, Xufang 👤 St John, Sarah E. 👤 Osswald, Heather L. 👤 O'Brien, Amornrat 👤 Banach, Bridget S. 👤 Sleeman, Katrina 👤 Ghosh, Arun K. 👤 Mesecar, Andrew D. 👤 Baker, Susan C. ⏰ 2014 📚 Journal of Virology

• Characterization of a critical interaction between the coronavirus nucleocapsid protein and nonstructural protein 3 of the viral replicase-transcriptase complex

  👤 Hurst, Kelley R. 👤 Koetzner, Cheri A. 👤 Masters, Paul S. ⏰ 2013 📚 Journal of Virology

• SARS-coronavirus replication is supported by a reticulovesicular network of modified endoplasmic reticulum

  👤 Knoops, Kèvin 👤 Kikkert, Marjolein 👤 Van Den Worm, Sjoerd H.E. 👤 Zevenhoven-Dobbe, Jessika C. 👤 Van Der Meer, Yvonne 👤 Koster, Abraham J. 👤 Mommaas, A. Mieke 👤 Snijder, Eric J. ⏰ 2008 📚 PLoS Biology

• Functional analysis of the murine coronavirus genomic RNA packaging signal

  👤 Kuo, Lili 👤 Masters, Paul S. ⏰ 2013 📚 Journal of Virology

• Selectivity in ISG15 and ubiquitin recognition by the SARS coronavirus papain-like protease

  👤 Lindner, Holger A. 👤 Lytvyn, Viktoria 👤 Qi, Hongtao 👤 Lachance, Paule 👤 Ziomek, Edmund 👤 Ménard, Robert ⏰ 2007 📚 Archives of Biochemistry and Biophysics

• RNA structure analysis of alphacoronavirus terminal genome regions

  👤 Madhugiri, Ramakanth 👤 Fricke, Markus 👤 Marz, Manja 👤 Ziebuhr, John ⏰ 2014 📚 Virus Research

• Discovery of an RNA virus 3′→5′ exoribonuclease that is critically involved in coronavirus RNA synthesis

  👤 Minskaia, Ekaterina 👤 Hertzig, Tobias 👤 Gorbalenya, Alexander E. 👤 Campanacci, Valérie 👤 Cambillau, Christian 👤 Canard, Bruno 👤 Ziebuhr, John ⏰ 2006 📚 Proceedings of the National Academy of Sciences of the United States of America

• Antisense morpholino-oligomers directed against the 5′ end of the genome inhibit coronavirus proliferation and growth

  👤 Neuman, Benjamin W. 👤 Stein, David A. 👤 Kroeker, Andrew D. 👤 Paulino, Amy D. 👤 Moulton, Hong M. 👤 Iversen, Patrick L. 👤 Buchmeier, Michael J. ⏰ 2004 📚 Journal of Virology

• Functional and genetic analysis of coronavirus replicase-transcriptase proteins

  👤 Sawicki, Stanley G. 👤 Sawicki, Dorothea L. 👤 Younker, Diane 👤 Meyer, Yvonne 👤 Thiel, Volker 👤 Stokes, Helen 👤 Siddell, Stuart G. ⏰ 2005 📚 PLoS Pathogens

• Binding site-based classification of coronaviral papain-like proteases

  👤 Sulea, Traian 👤 Lindner, Holger A. 👤 Purisima, Enrico O. 👤 Ménard, Robert ⏰ 2006 📚 Proteins: Structure, Function and Genetics

• Coronavirus papain-like proteases negatively regulate antiviral innate immune response through disruption of STING-mediated signaling

  👤 Sun, Li 👤 Xing, Yaling 👤 Chen, Xiaojuan 👤 Zheng, Yang 👤 Yang, Yudong 👤 Nichols, Daniel B. 👤 Clementz, Mark A. 👤 Banach, Bridget S. 👤 Li, Kui 👤 Baker, Susan C. 👤 Chen, Zhongbin ⏰ 2012 📚 PLoS ONE

• Binding of the 50-untranslated region of coronavirus RNA to zinc finger CCHC-type and RNA-binding motif 1 enhances viral replication and transcription

  👤 Tan, Yong Wah 👤 Hong, Wanjin 👤 Liu, Ding Xiang ⏰ 2012 📚 Nucleic Acids Research