๐ Plp2
Articles (16)
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X-ray structural and biological evaluation of a series of potent and highly selective inhibitors of human coronavirus papain-like proteases
๐ค Bรกez-Santos, Yahira M. ๐ค Barraza, Scott J. ๐ค Wilson, Michael W. ๐ค Agius, Michael P. ๐ค Mielech, Anna M. ๐ค Davis, Nicole M. ๐ค Baker, Susan C. ๐ค Larsen, Scott D. ๐ค Mesecar, Andrew D. โฐ 2014 ๐ Journal of Medicinal Chemistry
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Coronavirus membrane-associated papain-like proteases induce autophagy through interacting with Beclin1 to negatively regulate antiviral innate immunity
๐ค Chen, Xiaojuan ๐ค Wang, Kai ๐ค Xing, Yaling ๐ค Tu, Jian ๐ค Yang, Xingxing ๐ค Zhao, Qian ๐ค Li, Kui ๐ค Chen, Zhongbin โฐ 2014 ๐ Protein and Cell
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Proteolytic processing and deubiquitinating activity of papain-like proteases of human coronavirus NL63
๐ค Chen, Zhongbin ๐ค Wang, Yanhua ๐ค Ratia, Kiira ๐ค Mesecar, Andrew D. ๐ค Wilkinson, Keith D. ๐ค Baker, Susan C. โฐ 2007 ๐ Journal of Virology
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Deubiquitinating and interferon antagonism activities of coronavirus papain-like proteases
๐ค Clementz, Mark A. ๐ค Chen, Zhongbin ๐ค Banach, Bridget S. ๐ค Wang, Yanhua ๐ค Sun, Li ๐ค Ratia, Kiira ๐ค Baez-Santos, Yahira M. ๐ค Wang, Jie ๐ค Takayama, Jun ๐ค Ghosh, Arun K. ๐ค Li, Kui ๐ค Mesecar, Andrew D. ๐ค Baker, Susan C. โฐ 2010 ๐ Journal of Virology
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Structure-Guided Mutagenesis Alters Deubiquitinating Activity and Attenuates Pathogenesis of a Murine Coronavirus.
๐ค Deng, Xufang ๐ค Chen, Yafang ๐ค Mielech, Anna M ๐ค Hackbart, Matthew ๐ค Kesely, Kristina R ๐ค Mettelman, Robert C ๐ค O'Brien, Amornrat ๐ค Chapman, Mackenzie E ๐ค Mesecar, Andrew D ๐ค Baker, Susan C โฐ 2020 ๐ J Virol
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Analysis of coronavirus temperature-sensitive mutants reveals an interplay between the macrodomain and Papain-like protease impacting replication and pathogenesis
๐ค Deng, Xufang ๐ค Mettelman, Robert C. ๐ค O'Brien, Amornrat ๐ค Thompson, John A. ๐ค O'Brien, Timothy E. ๐ค Baker, Susan C. โฐ 2019 ๐ Journal of Virology
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Exchange of the coronavirus replicase polyprotein cleavage sites alters protease specificity and processing
๐ค Gadlage, Mark J. ๐ค Denison, Mark R. โฐ 2010 ๐ Journal of Virology
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Papain-like protease 2 (PLP2) from severe acute respiratory syndrome coronavirus (SARS-CoV): Expression, purification, characterization, and inhibition
๐ค Han, Yu San ๐ค Chang, Gu Gang ๐ค Juo, Chiun Gung ๐ค Lee, Hong Jen ๐ค Yen, Shiou Hwei ๐ค Hsu, John Tsu An ๐ค Chen, Xin โฐ 2005 ๐ Biochemistry
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Membrane topology of murine coronavirus replicase nonstructural protein 3
๐ค Kanjanahaluethai, Amornrat ๐ค Chen, Zhongbin ๐ค Jukneliene, Dalia ๐ค Baker, Susan C. โฐ 2007 ๐ Virology
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Identification of the murine coronavirus MP1 cleavage site recognized by papain-like proteinase 2
๐ค Kanjanahaluethai, Amornrat ๐ค Jukneliene, Dalia ๐ค Baker, Susan C. โฐ 2003 ๐ Journal of Virology
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Protein interferon-stimulated gene 15 conjugation delays but does not overcome coronavirus proliferation in a model of fulminant hepatitis
๐ค Ma, Xue Zhong ๐ค Bartczak, Agata ๐ค Zhang, Jianhua ๐ค He, Wei ๐ค Shalev, Itay ๐ค Smil, David ๐ค Chen, Limin ๐ค Phillips, Jim ๐ค Feld, Jordan J. ๐ค Selzner, Nazia ๐ค Levy, Gary ๐ค McGilvray, Ian โฐ 2014 ๐ Journal of Virology
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Murine coronavirus ubiquitin-like domain is important for papain-like protease stability and viral pathogenesis
๐ค Mielech, Anna M. ๐ค Deng, Xufang ๐ค Chen, Yafang ๐ค Kindler, Eveline ๐ค Wheeler, Dorthea L. ๐ค Mesecar, Andrew D. ๐ค Thiel, Volker ๐ค Perlman, Stanley ๐ค Baker, Susan C. โฐ 2015 ๐ Journal of Virology
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Coronavirus papain-like proteases negatively regulate antiviral innate immune response through disruption of STING-mediated signaling
๐ค Sun, Li ๐ค Xing, Yaling ๐ค Chen, Xiaojuan ๐ค Zheng, Yang ๐ค Yang, Yudong ๐ค Nichols, Daniel B. ๐ค Clementz, Mark A. ๐ค Banach, Bridget S. ๐ค Li, Kui ๐ค Baker, Susan C. ๐ค Chen, Zhongbin โฐ 2012 ๐ PLoS ONE
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Structural and biochemical characterization of SADS-CoV papain-like protease 2.
๐ค Wang, Lu ๐ค Hu, Weihua ๐ค Fan, Chengpeng โฐ 2020 ๐ Protein Sci
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Proteolytic processing, deubiquitinase and interferon antagonist activities of Middle East respiratory syndrome coronavirus papain-like protease
๐ค Yang, Xingxing ๐ค Chen, Xiaojuan ๐ค Bian, Guangxing ๐ค Tu, Jian ๐ค Xing, Yaling ๐ค Wang, Yayun ๐ค Chen, Zhongbin โฐ 2014 ๐ Journal of General Virology
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P53 degradation by a coronavirus papain-like protease suppresses type I interferon signaling
๐ค Yuan, Lin ๐ค Chen, Zhongbin ๐ค Song, Shanshan ๐ค Wang, Shan ๐ค Tian, Chunyan ๐ค Xing, Guichun ๐ค Chen, Xiaojuan ๐ค Xiao, Zhi Xiong ๐ค He, Fuchu ๐ค Zhang, Lingqiang โฐ 2015 ๐ Journal of Biological Chemistry