🔗 Virulence

Articles (149)

• Genomic and single nucleotide polymorphism analysis of infectious bronchitis coronavirus

  👤 Abolnik, Celia ⏰ 2015 📚 Infection, Genetics and Evolution

• A mouse model for Betacoronavirus subgroup 2c using a bat coronavirus strain HKU5 variant

  👤 Agnihothram, Sudhakar 👤 Yount Jr., Boyd L. 👤 Donaldson, Eric F. 👤 Huynh, Jeremy 👤 Menachery, Vineet D. 👤 Gralinski, Lisa E. 👤 Graham, Rachel L. 👤 Becker, Michelle M. 👤 Tomar, Sakshi 👤 Scobey, Trevor D. 👤 Osswald, Heather L. 👤 Whitmore, Alan 👤 Gopal, Robin 👤 Ghosh, Arun K. 👤 Mesecar, Andrew 👤 Zambon, Maria 👤 Heise, Mark 👤 Denison, Mark R. 👤 Baric, Ralph S. ⏰ 2014 📚 mBio

• Coronavirus susceptibility to the antiviral remdesivir (GS-5734) is mediated by the viral polymerase and the proofreading exoribonuclease

  👤 Agostini, Maria L. 👤 Andres, Erica L. 👤 Sims, Amy C. 👤 Graham, Rachel L. 👤 Sheahan, Timothy P. 👤 Lu, Xiaotao 👤 Smith, Everett Clinton 👤 Case, James Brett 👤 Feng, Joy Y. 👤 Jordan, Robert 👤 Ray, Adrian S. 👤 Cihlar, Tomas 👤 Siegel, Dustin 👤 Mackman, Richard L. 👤 Clarke, Michael O. 👤 Baric, Ralph S. 👤 Denison, Mark R. ⏰ 2018 📚 mBio

• Selective packaging in murine coronavirus promotes virulence by limiting type I interferon responses

  👤 Athmer, Jeremiah 👤 Fehr, Anthony R. 👤 Grunewald, Matthew E. 👤 Qu, Wen 👤 Wheeler, D. Lori 👤 Graepel, Kevin W. 👤 Channappanavar, Rudragouda 👤 Sekine, Aimee 👤 Aldabeeb, Dana Saud 👤 Gale, Michael 👤 Denison, Mark R. 👤 Perlman, Stanley ⏰ 2018 📚 mBio

• Quasispecies composition and phylogenetic analysis of feline coronaviruses (FCoVs) in naturally infected cats

  👤 Battilani, Mara 👤 Coradin, Tiziana 👤 Scagliarini, Alessandra 👤 Ciulli, Sara 👤 Ostanello, Fabio 👤 Prosperi, Santino 👤 Morganti, Luigi ⏰ 2003 📚 FEMS Immunology and Medical Microbiology

• Pathogenesis of murine coronavirus in the central nervous system

  👤 Bender, Susan J. 👤 Weiss, Susan R. ⏰ 2010 📚 Journal of Neuroimmune Pharmacology

• Prevalence of feline coronavirus types I and II in cats with histopathologically verified feline infectious peritonitis

  👤 Benetka, Viviane 👤 Kübber-Heiss, Anna 👤 Kolodziejek, Jolanta 👤 Nowotny, Norbert 👤 Hofmann-Parisot, Margarete 👤 Möstl, Karin ⏰ 2004 📚 Veterinary Microbiology

• Expression, purification and characterization of recombinant severe acute respiratory syndrome coronavirus non-structural protein 1

  👤 Brucz, Kimberly 👤 Miknis, Zachary J. 👤 Schultz, L. Wayne 👤 Umland, Timothy C. ⏰ 2007 📚 Protein Expression and Purification

• Murine encephalitis caused by HCoV-OC43, a human coronavirus with broad species specificity, is partly immune-mediated

  👤 Butler, Noah 👤 Pewe, Lecia 👤 Trandem, Kathryn 👤 Perlman, Stanley ⏰ 2006 📚 Virology

• Proteomics analysis of differentially expressed proteins in chicken trachea and kidney after infection with the highly virulent and attenuated coronavirus infectious bronchitis virus in vivo

  👤 Cao, Zhongzan 👤 Han, Zongxi 👤 Shao, Yuhao 👤 Liu, Xiaoli 👤 Sun, Junfeng 👤 Yu, Demin 👤 Kong, Xiangang 👤 Liu, Shengwang ⏰ 2012 📚 Proteome Science

• An exclusive 42 amino acid signature in pp1ab protein provides insights into the evolutive history of the 2019 novel human-pathogenic coronavirus (SARS-CoV-2).

  👤 Cardenas-Conejo, Yair 👤 Linan-Rico, Andromeda 👤 Garcia-Rodriguez, Daniel Alejandro 👤 Centeno-Leija, Sara 👤 Serrano-Posada, Hugo ⏰ 2020 📚 J Med Virol

• Role of severe acute respiratory syndrome coronavirus viroporins E, 3a, and 8a in replication and pathogenesis

  👤 Castaño-Rodriguez, Carlos 👤 Honrubia, Jose M. 👤 Gutiérrez-Álvarez, Javier 👤 DeDiego, Marta L. 👤 Nieto-Torres, Jose L. 👤 Jimenez-Guardeño, Jose M. 👤 Regla-Nava, Jose A. 👤 Fernandez-Delgado, Raul 👤 Verdia-Báguena, Carmina 👤 Queralt-Martín, Maria 👤 Kochan, Grazyna 👤 Perlman, Stanley 👤 Aguilella, Vicente M. 👤 Sola, Isabel 👤 Enjuanes, Luis ⏰ 2018 📚 mBio

• The emerging novel Middle East respiratory syndrome coronavirus: The "knowns" and "unknowns"

  👤 Chan, Jasper Fuk Woo 👤 Lau, Susanna Kar Pui 👤 Woo, Patrick Chiu Yat ⏰ 2013 📚 Journal of the Formosan Medical Association

• Feline infectious peritonitis: Insights into feline coronavirus pathobiogenesis and epidemiology based on genetic analysis of the viral 3c gene

  👤 Chang, Hui Wen 👤 de Groot, Raoul J. 👤 Egberink, Herman F. 👤 Rottier, Peter J.M. ⏰ 2010 📚 Journal of General Virology

• Quaternary structure of the severe acute respiratory syndrome (SARS) coronavirus main protease

  👤 Chou, Chi Yuan 👤 Chang, Hui Chuan 👤 Hsu, Wen Chi 👤 Lin, Tien Zheng 👤 Lin, Chao Hsiung 👤 Chang, Gu Gang ⏰ 2004 📚 Biochemistry

• Nucleotide and predicted amino acid sequences of all genes encoded by the 3' genomic portion (9.5 kb) of respiratory bovine coronaviruses and comparisons among respiratory and enteric coronaviruses

  👤 Chouljenko, Vladimir N. 👤 Kousoulas, Konstantin G. 👤 Lin, Xiaoqing 👤 Storz, Johannes ⏰ 1998 📚 Virus Genes

• Biopolymeric nano/microspheres for selective and reversible adsorption of coronaviruses

  👤 Ciejka, Justyna 👤 Wolski, Karol 👤 Nowakowska, Maria 👤 Pyrc, Krzysztof 👤 Szczubiałka, Krzysztof ⏰ 2017 📚 Materials Science and Engineering C

• The murine coronavirus nucleocapsid gene is a determinant of virulence

  👤 Cowley, Timothy J. 👤 Long, Simon Y. 👤 Weiss, Susan R. ⏰ 2010 📚 Journal of Virology

• Enhanced green fluorescent protein expression may be used to monitor murine coronavirus spread in vitro and in the mouse central nervous system

  👤 Das Sarma, Jayasri 👤 Scheen, Esther 👤 Seo, Su Hun 👤 Koval, Michael 👤 Weiss, Susan R. ⏰ 2002 📚 Journal of NeuroVirology

• Comparison of bovine coronavirus isolates associated with neonatal calf diarrhoea and winter dysentery in adult dairy cattle in Quebec

  👤 Dea, S. 👤 Michaud, L. 👤 Milane, G. ⏰ 1995 📚 Journal of General Virology

• Coronavirus virulence genes with main focus on SARS-CoV envelope gene

  👤 DeDiego, Marta L. 👤 Nieto-Torres, Jose L. 👤 Jimenez-Guardeño, Jose M. 👤 Regla-Nava, Jose A. 👤 Castaño-Rodriguez, Carlos 👤 Fernandez-Delgado, Raul 👤 Usera, Fernando 👤 Enjuanes, Luis ⏰ 2014 📚 Virus Research

• Inhibition of NF-κB-mediated inflammation in severe acute respiratory syndrome coronavirus-infected mice increases survival

  👤 DeDiego, Marta L. 👤 Nieto-Torres, Jose L. 👤 Regla-Nava, Jose A. 👤 Jimenez-Guardeño, Jose M. 👤 Fernandez-Delgado, Raul 👤 Fett, Craig 👤 Castaño-Rodriguez, Carlos 👤 Perlman, Stanley 👤 Enjuanes, Luis ⏰ 2014 📚 Journal of Virology

• Pathogenicity of severe acute respiratory coronavirus deletion mutants in hACE-2 transgenic mice

  👤 DeDiego, Marta L. 👤 Pewe, Lecia 👤 Alvarez, Enrique 👤 Rejas, Maria Teresa 👤 Perlman, Stanley 👤 Enjuanes, Luis ⏰ 2008 📚 Virology

• Structure-Guided Mutagenesis Alters Deubiquitinating Activity and Attenuates Pathogenesis of a Murine Coronavirus.

  👤 Deng, Xufang 👤 Chen, Yafang 👤 Mielech, Anna M 👤 Hackbart, Matthew 👤 Kesely, Kristina R 👤 Mettelman, Robert C 👤 O'Brien, Amornrat 👤 Chapman, Mackenzie E 👤 Mesecar, Andrew D 👤 Baker, Susan C ⏰ 2020 📚 J Virol

• Analysis of coronavirus temperature-sensitive mutants reveals an interplay between the macrodomain and Papain-like protease impacting replication and pathogenesis

  👤 Deng, Xufang 👤 Mettelman, Robert C. 👤 O'Brien, Amornrat 👤 Thompson, John A. 👤 O'Brien, Timothy E. 👤 Baker, Susan C. ⏰ 2019 📚 Journal of Virology

• Coronavirus endoribonuclease activity in porcine epidemic diarrhea virus suppresses type I and type III interferon responses

  👤 Deng, Xufang 👤 Van Geelen, Albert 👤 Buckley, Alexandra C. 👤 O’Brien, Amornrat 👤 Pillatzki, Angela 👤 Lager, Kelly M. 👤 Faaberg, Kay S. 👤 Baker, Susan C. ⏰ 2019 📚 Journal of Virology

• Severe acute respiratory syndrome coronavirus pathogenesis, disease and vaccines: An update

  👤 Denison, Mark R. ⏰ 2004 📚 Pediatric Infectious Disease Journal

• The tetraspanin CD9 facilitates MERS-coronavirus entry by scaffolding host cell receptors and proteases

  👤 Earnest, James T. 👤 Hantak, Michael P. 👤 Li, Kun 👤 McCray, Paul B. 👤 Perlman, Stanley 👤 Gallagher, Tom ⏰ 2017 📚 PLoS Pathogens

• Reverse genetics for type I feline coronavirus field isolate to study the molecular pathogenesis of feline infectious peritonitis

  👤 Ehmann, Rosina 👤 Kristen-Burmann, Claudia 👤 Bank-Wolf, Barbara 👤 König, Matthias 👤 Herden, Christiane 👤 Hain, Torsten 👤 Thiel, Heinz Jürgen 👤 Ziebuhr, John 👤 Tekes, Gergely ⏰ 2018 📚 mBio

• Feline coronavirus with and without spike gene mutations detected by real-time RT-PCRs in cats with feline infectious peritonitis

  👤 Emmler, Laura 👤 Felten, Sandra 👤 Matiasek, Kaspar 👤 Balzer, Hans Joerg 👤 Pantchev, Nikola 👤 Leutenegger, Christian 👤 Hartmann, Katrin ⏰ 2019 📚 Journal of Feline Medicine and Surgery

• The conserved coronavirus macrodomain promotes virulence and suppresses the innate immune response during severe acute respiratory syndrome coronavirus infection

  👤 Fehr, Anthony R. 👤 Channappanavar, Rudragouda 👤 Jankevicius, Gytis 👤 Fett, Craig 👤 Zhao, Jincun 👤 Athmer, Jeremiah 👤 Meyerholz, David K. 👤 Ahel, Ivan 👤 Perlman, Stanley ⏰ 2016 📚 mBio

• SARS coronavirus and innate immunity

  👤 Frieman, Matthew 👤 Heise, Mark 👤 Baric, Ralph ⏰ 2008 📚 Virus Research

• Molecular determinants of severe acute respiratory syndrome coronavirus pathogenesis and virulence in young and aged mouse models of human disease

  👤 Frieman, Matthew 👤 Yount, Boyd 👤 Agnihothram, Sudhakar 👤 Page, Carly 👤 Donaldson, Eric 👤 Roberts, Anjeanette 👤 Vogel, Leatrice 👤 Woodruff, Becky 👤 Scorpio, Diana 👤 Subbarao, Kanta 👤 Baric, Ralph S. ⏰ 2012 📚 Journal of Virology

• A combination of mutations in the S1 part of the spike glycoprotein gene of coronavirus MHV-A59 abolishes demyelination

  👤 Fu, Li 👤 Gonzales, Donna M. 👤 Das Sarma, Jayasri 👤 Lavi, Ehud ⏰ 2004 📚 Journal of NeuroVirology

• Fitness barriers limit reversion of a proofreading-deficient coronavirus

  👤 Graepel, Kevin W. 👤 Agostini, Maria L. 👤 Lu, Xiaotao 👤 Sexton, Nicole R. 👤 Denisona, Mark R. ⏰ 2019 📚 Journal of Virology

• Proofreading-deficient coronaviruses adapt for increased fitness over long-term passage without reversion of exoribonuclease-inactivating mutations

  👤 Graepel, Kevin W. 👤 Lu, Xiaotao 👤 Case, James Brett 👤 Sexton, Nicole R. 👤 Smith, Everett Clinton 👤 Denisona, Mark R. ⏰ 2017 📚 mBio

• A live, impaired-fidelity coronavirus vaccine protects in an aged, immunocompromised mouse model of lethal disease

  👤 Graham, Rachel L. 👤 Becker, Michelle M. 👤 Eckerle, Lance D. 👤 Bolles, Meagan 👤 Denison, Mark R. 👤 Baric, Ralph S. ⏰ 2012 📚 Nature Medicine

• SARS coronavirus replicase proteins in pathogenesis

  👤 Graham, Rachel L. 👤 Sparks, Jennifer S. 👤 Eckerle, Lance D. 👤 Sims, Amy C. 👤 Denison, Mark R. ⏰ 2008 📚 Virus Research

• The coronavirus macrodomain is required to prevent PARP-mediated inhibition of virus replication and enhancement of IFN expression

  👤 Grunewald, Matthew E. 👤 Chen, Yating 👤 Kuny, Chad 👤 Maejima, Takashi 👤 Lease, Robert 👤 Ferraris, Dana 👤 Aikawa, Masanori 👤 Sullivan, Christopher S. 👤 Perlman, Stanley 👤 Fehr, Anthony R. ⏰ 2019 📚 PLoS Pathogens

• Murine AKAP7 has a 2ʹ,5ʹ-phosphodiesterase domain that can complement an inactive murine coronavirus ns2 gene

  👤 Gusho, Elona 👤 Zhang, Rong 👤 Jha, Babal K. 👤 Thornbrough, Joshua M. 👤 Dong, Beihua 👤 Gaughan, Christina 👤 Elliott, Ruth 👤 Weiss, Susan R. 👤 Silverman, Robert H. ⏰ 2014 📚 mBio

• Papain-like protease 2 (PLP2) from severe acute respiratory syndrome coronavirus (SARS-CoV): Expression, purification, characterization, and inhibition

  👤 Han, Yu San 👤 Chang, Gu Gang 👤 Juo, Chiun Gung 👤 Lee, Hong Jen 👤 Yen, Shiou Hwei 👤 Hsu, John Tsu An 👤 Chen, Xin ⏰ 2005 📚 Biochemistry

• Is There an Association Between COVID-19 Mortality and the Renin-Angiotensin System-a Call for Epidemiologic Investigations.

  👤 Hanff, Thomas C 👤 Harhay, Michael O 👤 Brown, Tyler S 👤 Cohen, Jordana B 👤 Mohareb, Amir M ⏰ 2020 📚 Clin Infect Dis

• The molecular genetics of feline coronaviruses: Comparative sequence analysis of the ORF7a/7b transcription unit of different biotypes

  👤 Herrewegh, Arnold A.P.M. 👤 Vennema, Harry 👤 Horzinek, Marian C. 👤 Rottier, Peter J.M. 👤 De Groot, Raoul J. ⏰ 1995 📚 Virology

• Fourth European conference on infections in leukaemia (ECIL-4): Guidelines for diagnosis and treatment of human respiratory syncytial virus, parainfluenza virus, metapneumovirus, rhinovirus, and coronavirus

  👤 Hirsch, Hans H. 👤 Martino, Rodrigo 👤 Ward, Katherine N. 👤 Boeckh, Michael 👤 Einsele, Hermann 👤 Ljungman, Per ⏰ 2013 📚 Clinical Infectious Diseases

• 3C protein of feline coronavirus inhibits viral replication independently of the autophagy pathway

  👤 Hsieh, Li En 👤 Huang, Wei Pang 👤 Tang, Da Jay 👤 Wang, Ying Ting 👤 Chen, Ching Tang 👤 Chueh, Ling Ling ⏰ 2013 📚 Research in Veterinary Science

• Severe acute respiratory syndrome coronavirus protein 6 accelerates murine hepatitis virus infections by more than one mechanism

  👤 Hussain, Snawar 👤 Perlman, Stanley 👤 Gallagher, Thomas M. ⏰ 2008 📚 Journal of Virology

• Both spike and background genes contribute to murine coronavirus neurovirulence

  👤 Iacono, Kathryn T. 👤 Kazi, Lubna 👤 Weiss, Susan R. ⏰ 2006 📚 Journal of Virology

• Neutralizing antibody against severe acute respiratory syndrome (SARS)-coronavirus spike is highly effective for the protection of mice in the murine SARS model

  👤 Ishii, Koji 👤 Hasegawa, Hideki 👤 Nagata, Noriyo 👤 Ami, Yasushi 👤 Fukushi, Shuetsu 👤 Taguchi, Fumihiro 👤 Tsunetsugu-Yokota, Yasuko ⏰ 2009 📚 Microbiology and Immunology

• Natural products and their derivatives against coronavirus: A review of the non-clinical and pre-clinical data.

  👤 Islam, Muhammad Torequl 👤 Sarkar, Chandan 👤 El-Kersh, Dina M 👤 Jamaddar, Sarmin 👤 Uddin, Shaikh Jamal 👤 Shilpi, Jamil A 👤 Mubarak, Mohammad S ⏰ 2020 📚 Phytother Res

• Vacuolating encephalitis in mice infected by human coronavirus OC43

  👤 Jacomy, Hélène 👤 Talbot, Pierre J. ⏰ 2003 📚 Virology

• Feline coronavirus: Insights into viral pathogenesis based on the spike protein structure and function

  👤 Jaimes, Javier A. 👤 Whittaker, Gary R. ⏰ 2018 📚 Virology

• Elevated Plasmin(ogen) as a Common Risk Factor for COVID-19 Susceptibility.

  👤 Ji, Hong-Long 👤 Zhao, Runzhen 👤 Matalon, Sadis 👤 Matthay, Michael A ⏰ 2020 📚 Physiol Rev

• The PDZ-Binding Motif of Severe Acute Respiratory Syndrome Coronavirus Envelope Protein Is a Determinant of Viral Pathogenesis

  👤 Jimenez-Guardeño, Jose M. 👤 Nieto-Torres, Jose L. 👤 DeDiego, Marta L. 👤 Regla-Nava, Jose A. 👤 Fernandez-Delgado, Raul 👤 Castaño-Rodriguez, Carlos 👤 Enjuanes, Luis ⏰ 2014 📚 PLoS Pathogens

• Spongiform degeneration induced by neuropathogenic murine coronavirus infection

  👤 Kashiwazaki, Hiromi 👤 Nomura, Risa 👤 Matsuyama, Shutoku 👤 Taguchi, Fumihiro 👤 Watanabe, Rihito ⏰ 2011 📚 Pathology International

• Analysis of genetic mutations in the 7a7b open reading frame of coronavirus of cheetahs (Acinonyx jubatus)

  👤 Kennedy, Melissa A. 👤 Moore, Emily 👤 Wilkes, Rebecca P. 👤 Citino, Scott B. 👤 Kania, Stephen A. ⏰ 2006 📚 American Journal of Veterinary Research

• Ribavirin and interferon-α2b as primary and preventive treatment for Middle East respiratory syndrome coronavirus: A preliminary report of two cases

  👤 Khalid, Mohammed 👤 Al Rabiah, Fahad 👤 Khan, Basha 👤 Al Mobeireek, Abdullah 👤 Butt, Taimur S. 👤 Al Mutairy, Eid ⏰ 2015 📚 Antiviral Therapy

• Molecular characterization and pathogenesis of transmissible gastroenteritis coronavirus (TGEV) and porcine respiratory coronavirus (PRCV) field isolates co-circulating in a swine herd

  👤 Kim, L. 👤 Hayes, J. 👤 Lewis, P. 👤 Parwani, A. V. 👤 Chang, K. O. 👤 Saif, L. J. ⏰ 2000 📚 Archives of Virology

• Sequential emergence and wide spread of neutralization escape middle east respiratory syndrome coronavirus mutants, South Korea, 2015

  👤 Kim, Yeon Sook 👤 Aigerim, Abdimadiyeva 👤 Park, Uni 👤 Kim, Yuri 👤 Rhee, Ji Young 👤 Choi, Jae Phil 👤 Park, Wan Beom 👤 Park, Sang Won 👤 Kim, Yeonjae 👤 Lim, Dong Gyun 👤 Inn, Kyung Soo 👤 Hwang, Eung Soo 👤 Choi, Myung Sik 👤 Shin, Hyoung Shik 👤 Cho, Nam Hyuk ⏰ 2019 📚 Emerging Infectious Diseases

• Reversal of the Progression of Fatal Coronavirus Infection in Cats by a Broad-Spectrum Coronavirus Protease Inhibitor

  👤 Kim, Yunjeong 👤 Liu, Hongwei 👤 Galasiti Kankanamalage, Anushka C. 👤 Weerasekara, Sahani 👤 Hua, Duy H. 👤 Groutas, William C. 👤 Chang, Kyeong Ok 👤 Pedersen, Niels C. ⏰ 2016 📚 PLoS Pathogens

• Spread of mutant middle east respiratory syndrome coronavirus with reduced affinity to human CD26 during the south Korean outbreak

  👤 Kim, Yuri 👤 Cheon, Shinhye 👤 Min, Chan Ki 👤 Sohn, Kyung Mok 👤 Kang, Ying Jin 👤 Cha, Young Je 👤 Kang, Ju Il 👤 Han, Seong Kyu 👤 Ha, Na Young 👤 Kim, Gwanghun 👤 Aigerim, Abdimadiyeva 👤 Shin, Hyun Mu 👤 Choi, Myung Sik 👤 Kim, Sanguk 👤 Cho, Hyun Soo 👤 Kim, Yeon Sook 👤 Choa, Nam Hyuk ⏰ 2016 📚 mBio

• Infectious bronchitis coronavirus limits interferon production by inducing a host shutoff that requires accessory protein 5b

  👤 Kint, Joeri 👤 Langereis, Martijn A. 👤 Maier, Helena J. 👤 Britton, Paul 👤 van Kuppeveld, Frank J. 👤 Koumans, Joseph 👤 Wiegertjes, Geert F. 👤 Forlenza, Maria ⏰ 2016 📚 Journal of Virology

• Preliminary studies on feline coronavirus distribution in naturally and experimentally infected cats

  👤 Kiss, I. 👤 Kecskeméti, S. 👤 Tanyi, J. 👤 Klingeborn, B. 👤 Belák, Sandor ⏰ 2000 📚 Research in Veterinary Science

• Epidemiological and Clinical Aspects of COVID-19; a Narrative Review.

  👤 Kolifarhood, Goodarz 👤 Aghaali, Mohammad 👤 Mozafar Saadati, Hossein 👤 Taherpour, Niloufar 👤 Rahimi, Sajjad 👤 Izadi, Neda 👤 Hashemi Nazari, Seyed Saeed ⏰ 2020 📚 Arch Acad Emerg Med

• PEDV and PDCoV pathogenesis: The interplay between host innate immune responses and porcine enteric coronaviruses

  👤 Koonpaew, Surapong 👤 Teeravechyan, Samaporn 👤 Frantz, Phanramphoei Namprachan 👤 Chailangkarn, Thanathom 👤 Jongkaewwattana, Anan ⏰ 2019 📚 Frontiers in Veterinary Science

• Comparison of mono- and co-infection by swine influenza A viruses and porcine respiratory coronavirus in porcine precision-cut lung slices

  👤 Krimmling, Tanja 👤 Schwegmann-Weßels, Christel ⏰ 2017 📚 Research in Veterinary Science

• Variations in disparate regions of the murine coronavirus spike protein impact the initiation of membrane fusion

  👤 Krueger, D. K. 👤 Kelly, S. M. 👤 Lewicki, D. N. 👤 Ruffolo, R. 👤 Gallagher, T. M. ⏰ 2001 📚 Journal of Virology

• Field Isolates of Transmissible Gastroenteritis Virus Differ at the Molecular Level from the Miller and Purdue Virulent and Attenuated Strains and from Porcine Respiratory Coronaviruses

  👤 Kwon, Hyuk Moo 👤 Saif, Linda J. 👤 Jackwood, Daral J. ⏰ 1998 📚 Journal of Veterinary Medical Science

• SARS virus: The beginning of the unraveling of a new coronavirus

  👤 Lai, Michael M.C. ⏰ 2003 📚 Journal of Biomedical Science

• Characterization of monoclonal antibodies against feline coronavirus accessory protein 7b

  👤 Lemmermeyer, Tanja 👤 Lamp, Benjamin 👤 Schneider, Rainer 👤 Ziebuhr, John 👤 Tekes, Gergely 👤 Thiel, Heinz Jürgen ⏰ 2016 📚 Veterinary Microbiology

• Extremely low exposure of a community to severe acute respiratory syndrome coronavirus: False seropositivity due to use of bacterially derived antigens

  👤 Leung, D. T.M. 👤 Van Maren, W. W.C. 👤 Chan, F. K.L. 👤 Chan, W. S. 👤 Lo, A. W.I. 👤 Ma, C. H. 👤 Tam, F. C.H. 👤 To, K. F. 👤 Chan, P. K.S. 👤 Sung, J. J.Y. 👤 Lim, P. L. ⏰ 2006 📚 Journal of Virology

• Structure-based preliminary analysis of immunity and virulence of SARS coronavirus

  👤 Li, Yan 👤 Luo, Chunqing 👤 Li, Wei 👤 Xu, Zhao 👤 Zeng, Changqing 👤 Bi, Shenli 👤 Yu, Jun 👤 Wu, Jun 👤 Yang, Huanming ⏰ 2004 📚 Viral Immunology

• Coronavirus Neurovirulence Correlates with the Ability of the Virus to Induce Proinflammatory Cytokine Signals from Astrocytes and Microglia

  👤 Li, Yun 👤 Fu, Li 👤 Gonzales, Donna M. 👤 Lavi, Ehud ⏰ 2004 📚 Journal of Virology

• Field strain feline coronaviruses with small deletions in ORF7b associated with both enteric infection and feline infectious peritonitis

  👤 Lin, Chao Nan 👤 Su, Bi Ling 👤 Huang, Hui Pi 👤 Lee, Jih Jong 👤 Hsieh, Min Wei 👤 Chueh, Ling Ling ⏰ 2009 📚 Journal of Feline Medicine and Surgery

• Origin and characteristics of the recombinant novel avian infectious bronchitis coronavirus isolate ck/CH/LJL/111054

  👤 Liu, Shengwang 👤 Xu, Qianqian 👤 Han, Zongxi 👤 Liu, Xiaoli 👤 Li, Huixin 👤 Guo, Hongbo 👤 Sun, Nana 👤 Shao, Yuhao 👤 Kong, Xiangang ⏰ 2014 📚 Infection, Genetics and Evolution

• Feline coronavirus quantitative reverse transcriptase polymerase chain reaction on effusion samples in cats with and without feline infectious peritonitis

  👤 Longstaff, Louise 👤 Porter, Emily 👤 Crossley, Victoria J. 👤 Hayhow, Sophie E. 👤 Helps, Christopher R. 👤 Tasker, Séverine ⏰ 2017 📚 Journal of Feline Medicine and Surgery

• Origin, evolution, and virulence of porcine deltacoronaviruses in the United States

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• Contributions of the viral genetic background and a single amino acid substitution in an immunodominant CD8+ T-cell epitope to murine coronavirus neurovirulence

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• Molecular and phylogenetic analysis of bovine coronavirus based on the spike glycoprotein gene

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• Attenuation and restoration of severe acute respiratory syndrome coronavirus mutant lacking 2'-o-methyltransferase activity

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• The spike glycoprotein of murine coronavirus MHV-JHM mediates receptor-independent infection and spread in the central nervous systems of Ceacam1a-/- mice

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• Computational studies of drug repurposing and synergism of lopinavir, oseltamivir and ritonavir binding with SARS-CoV-2 Protease against COVID-19.

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• Participation of both host and virus factors in induction of Severe Acute Respiratory Syndrome (SARS) in F344 rats infected with SARS coronavirus

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• The endonucleolytic RNA cleavage function of nsp1 of middle east respiratory syndrome coronavirus promotes the production of infectious virus particles in specific human cell lines

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• Severe acute respiratory syndrome coronavirus nsp1 suppresses host gene expression, including that of type I interferon, in infected cells

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• SARS coronavirus accessory proteins

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• Immunization with an attenuated severe acute respiratory syndrome coronavirus deleted in E protein protects against lethal respiratory disease

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• Enhancement of murine coronavirus replication by severe acute respiratory syndrome coronavirus protein 6 requires the N-terminal hydrophobic region but not C-terminal sorting motifs

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• The papain-like protease determines a virulence trait that varies among members of the SARS-coronavirus species

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• Severe Acute Respiratory Syndrome Coronavirus Envelope Protein Ion Channel Activity Promotes Virus Fitness and Pathogenesis

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• Severe acute respiratory syndrome coronavirus E protein transports calcium ions and activates the NLRP3 inflammasome

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• Enhanced virulence mediated by the murine coronavirus, mouse hepatitis virus strain JHM, is associated with a glycine at residue 310 of the spike glycoprotein

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• Transmissible gastroenteritis coronavirus gene 7 is not essential but influences in vivo virus replication and virulence

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• Full-genome evolutionary analysis of the novel corona virus (2019-nCoV) rejects the hypothesis of emergence as a result of a recent recombination event.

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• Proteolytic processing of middle east respiratory syndrome coronavirus spikes expands virus tropism

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• An outbreak of human coronavirus OC43 infection and serological cross-reactivity with SARS coronavirus

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• A severe acute respiratory syndrome-associated coronavirus-specific protein enhances virulence of an attenuated murine coronavirus

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• Reverse genetic characterization of the natural genomic deletion in SARS-Coronavirus strain Frankfurt-1 open reading frame 7b reveals an attenuating function of the 7b protein in-vitro and in-vivo

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• Multiple regions of the murine coronavirus spike glycoprotein influence neurovirulence

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• Murine coronavirus spike glycoprotein mediates degree of viral spread, inflammation, and virus-induced immunopathology in the central nervous system

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• Pathogenesis of neurotropic murine coronavirus is multifactorial

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• A mouse-adapted SARS-coronavirus causes disease and mortality in BALB/c mice

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• Escape from human monoclonal antibody neutralization affects in vitro and in vivo fitness of severe acute respiratory syndrome coronavirus

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• High secretion of interferons by human plasmacytoid dendritic cells upon recognition of middle east respiratory syndrome coronavirus

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• A conserved region of nonstructural protein 1 from alphacoronaviruses inhibits host gene expression and is critical for viral virulence

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• Single-amino-acid substitutions in open reading frame (ORF) 1b-nsp14 and ORF 2a proteins of the coronavirus mouse hepatitis virus are attenuating in mice

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• Recovery of a neurovirulent human coronavirus OC43 from an infectious cDNA clone

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• The OC43 human coronavirus envelope protein is critical for infectious virus production and propagation in neuronal cells and is a determinant of neurovirulence and CNS pathology

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• Phylogenetic analysis of infectious bronchitis coronaviruses newly isolated in China, and pathogenicity and evaluation of protection induced by Massachusetts serotype H120 vaccine against QX-like strains

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