🔗 Antiviral
Articles (546)
- [Expert consensus on chloroquine phosphate for the treatment of novel coronavirus pneumonia].
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Beta-cyclodextrin derivatives as carriers to enhance the antiviral activity of an antisense oligonucleotide directed toward a coronavirus intergenic consensus sequence
👤 Abdou, S. 👤 Collomb, J. 👤 Sallas, F. 👤 Marsura, A. 👤 Finance, C. ⏰ 1997 📚 Archives of Virology
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Overexpression of the nucleocapsid protein of Middle East respiratory syndrome coronavirus up-regulates CXCL10
👤 Aboagye, James Odame 👤 Yew, Chow Wenn 👤 Ng, Oi Wing 👤 Monteil, Vanessa M. 👤 Mirazimi, Ali 👤 Tan, Yee Joo ⏰ 2018 📚 Bioscience Reports
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Computational modeling of the bat HKU4 coronavirus 3CLpro inhibitors as a tool for the development of antivirals against the emerging Middle East respiratory syndrome (MERS) coronavirus
👤 Abuhammad, Areej 👤 Al-Aqtash, Rua'a A. 👤 Anson, Brandon J. 👤 Mesecar, Andrew D. 👤 Taha, Mutasem O. ⏰ 2017 📚 Journal of Molecular Recognition
- Use of a reverse-transcriptase polymerase chain reaction for monitoring the shedding of feline coronavirus by healthy cats
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Severe acute respiratory syndrome coronavirus replication inhibitor that interferes with the nucleic acid unwinding of the viral helicase
👤 Adedeji, Adeyemi O. 👤 Singh, Kamalendra 👤 Calcaterra, Nicholas E. 👤 DeDiego, Marta L. 👤 Enjuanes, Luis 👤 Weiss, Susan 👤 Sarafianos, Stefan G. ⏰ 2012 📚 Antimicrobial Agents and Chemotherapy
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Epidemiology, causes, clinical manifestation and diagnosis, prevention and control of coronavirus disease (COVID-19) during the early outbreak period: a scoping review.
👤 Adhikari, Sasmita Poudel 👤 Meng, Sha 👤 Wu, Yu-Ju 👤 Mao, Yu-Ping 👤 Ye, Rui-Xue 👤 Wang, Qing-Zhi 👤 Sun, Chang 👤 Sylvia, Sean 👤 Rozelle, Scott 👤 Raat, Hein 👤 Zhou, Huan ⏰ 2020 📚 Infect Dis Poverty
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Coronavirus susceptibility to the antiviral remdesivir (GS-5734) is mediated by the viral polymerase and the proofreading exoribonuclease
👤 Agostini, Maria L. 👤 Andres, Erica L. 👤 Sims, Amy C. 👤 Graham, Rachel L. 👤 Sheahan, Timothy P. 👤 Lu, Xiaotao 👤 Smith, Everett Clinton 👤 Case, James Brett 👤 Feng, Joy Y. 👤 Jordan, Robert 👤 Ray, Adrian S. 👤 Cihlar, Tomas 👤 Siegel, Dustin 👤 Mackman, Richard L. 👤 Clarke, Michael O. 👤 Baric, Ralph S. 👤 Denison, Mark R. ⏰ 2018 📚 mBio
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Small-Molecule Antiviral β-d-N4-Hydroxycytidine Inhibits a Proofreading-Intact Coronavirus with a High Genetic Barrier to Resistance
👤 Agostini, Maria L. 👤 Pruijssers, Andrea J. 👤 Chappell, James D. 👤 Gribble, Jennifer 👤 Lu, Xiaotao 👤 Andres, Erica L. 👤 Bluemling, Gregory R. 👤 Lockwood, Mark A. 👤 Sheahan, Timothy P. 👤 Sims, Amy C. 👤 Natchus, Michael G. 👤 Saindane, Manohar 👤 Kolykhalov, Alexander A. 👤 Painter, George R. 👤 Baric, Ralph S. 👤 Denison, Mark R. ⏰ 2019 📚 Journal of virology
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Generation of a transgenic mouse model of middle east respiratory syndrome coronavirus infection and disease
👤 Agrawal, Anurodh Shankar 👤 Garron, Tania 👤 Tao, Xinrong 👤 Peng, Bi Hung 👤 Wakamiya, Maki 👤 Chan, Teh Sheng 👤 Couch, Robert B. 👤 Tseng, Chien Te K. ⏰ 2015 📚 Journal of Virology
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Interference of ribosomal frameshifting by antisense peptide nucleic acids suppresses SARS coronavirus replication
👤 Ahn, Dae Gyun 👤 Lee, Wooseong 👤 Choi, Jin Kyu 👤 Kim, Seong Jun 👤 Plant, Ewan P. 👤 Almazán, Fernando 👤 Taylor, Deborah R. 👤 Enjuanes, Luis 👤 Oh, Jong Won ⏰ 2011 📚 Antiviral Research
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Ribavirin and interferon therapy in patients infected with the Middle East respiratory syndrome coronavirus: An observational study
👤 Al-Tawfiq, Jaffar A. 👤 Momattin, Hisham 👤 Dib, Jean 👤 Memish, Ziad A. ⏰ 2014 📚 International Journal of Infectious Diseases
- Vaccines against Middle East respiratory syndrome coronavirus for humans and camels
- Current knowledge about the antivirals remdesivir (GS-5734) and GS-441524 as therapeutic options for coronaviruses.
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Update on SARS research and other possibly zoonotic coronaviruses
👤 Anderson, Larry J. 👤 Tong, Suxiang ⏰ 2010 📚 International Journal of Antimicrobial Agents
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The Randomized Embedded Multifactorial Adaptive Platform for Community-acquired Pneumonia (REMAP-CAP) Study: Rationale and Design.
👤 Angus, Derek C 👤 Berry, Scott 👤 Lewis, Roger J 👤 Al-Beidh, Farah 👤 Arabi, Yaseen 👤 van Bentum-Puijk, Wilma 👤 Bhimani, Zahra 👤 Bonten, Marc 👤 Broglio, Kristine 👤 Brunkhorst, Frank 👤 Cheng, Allen C 👤 Chiche, Jean-Daniel 👤 De Jong, Menno 👤 Detry, Michelle 👤 Goossens, Herman 👤 Gordon, Anthony 👤 Green, Cameron 👤 Higgins, Alisa M 👤 Hullegie, Sebastiaan J 👤 Kruger, Peter 👤 Lamontagne, Francois 👤 Litton, Edward 👤 Marshall, John 👤 McGlothlin, Anna 👤 McGuinness, Shay 👤 Mouncey, Paul 👤 Murthy, Srinivas 👤 Nichol, Alistair 👤 O'Neill, Genevieve K 👤 Parke, Rachael 👤 Parker, Jane 👤 Rohde, Gernot 👤 Rowan, Kathryn 👤 Turner, Anne 👤 Young, Paul 👤 Derde, Lennie 👤 McArthur, Colin 👤 Webb, Steven A ⏰ 2020 📚 Ann Am Thorac Soc
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Effect of small interfering RNAs on in vitro replication and gene expression of feline coronavirus
👤 Anis, Eman A. 👤 Wilkes, Rebecca P. 👤 Kania, Stephen A. 👤 Legendre, Alfred M. 👤 Kennedy, Melissa A. ⏰ 2014 📚 American Journal of Veterinary Research
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Binding of the methyl donor S-adenosyl-Lmethionine to Middle East respiratory syndrome coronavirus 2'-Omethyltransferase nsp16 promotes recruitment of the allosteric activator nsp10
👤 Aouadi, Wahiba 👤 Blanjoie, Alexandre 👤 Vasseur, Jean Jacques 👤 Debart, Françoise 👤 Canard, Bruno 👤 Decroly, Etienne ⏰ 2017 📚 Journal of Virology
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Synthesis and anti-coronavirus activity of a series of 1-thia-4-azaspiro[4.5]decan-3-one derivatives
👤 Apaydın, Çağla Begüm 👤 Cesur, Nesrin 👤 Stevaert, Annelies 👤 Naesens, Lieve 👤 Cesur, Zafer ⏰ 2019 📚 Archiv der Pharmazie
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Critical care management of adults with community-acquired severe respiratory viral infection.
👤 Arabi, Yaseen M 👤 Fowler, Robert 👤 Hayden, Frederick G ⏰ 2020 📚 Intensive Care Med
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Development of broad-spectrum halomethyl ketone inhibitors against coronavirus main protease 3CLpro
👤 Bacha, Usman 👤 Barrila, Jennifer 👤 Gabelli, Sandra B. 👤 Kiso, Yoshiaki 👤 Mario Amzel, L. 👤 Freire, Ernesto ⏰ 2008 📚 Chemical Biology and Drug Design
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Natural small molecules as inhibitors of coronavirus lipid-dependent attachment to host cells: a possible strategy for reducing SARS-COV-2 infectivity?
👤 Baglivo, Mirko 👤 Baronio, Manuela 👤 Natalini, Giuseppe 👤 Beccari, Tommaso 👤 Chiurazzi, Pietro 👤 Fulcheri, Ezio 👤 Petralia, Paolo Pietro 👤 Michelini, Sandro 👤 Fiorentini, Giovanni 👤 Miggiano, Giacinto Abele 👤 Morresi, Assunta 👤 Tonini, Gerolamo 👤 Bertelli, Matteo ⏰ 2020 📚 Acta Biomed
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Crystal structure of the middle east respiratory syndrome coronavirus (MERS-CoV) papain-like protease bound to ubiquitin facilitates targeted disruption of deubiquitinating activity to demonstrate its role in innate immune suppression
👤 Bailey-Elkin, Ben A. 👤 Knaap, Robert C.M. 👤 Johnson, Garrett G. 👤 Dalebout, Tim J. 👤 Ninaber, Dennis K. 👤 Van Kasteren, Puck B. 👤 Bredenbeek, Peter J. 👤 Snijder, Eric J. 👤 Kikkert, Marjolein 👤 Mark, Brian L. ⏰ 2014 📚 Journal of Biological Chemistry
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Inhibition of feline (FIPV) and human (SARS) coronavirus by semisynthetic derivatives of glycopeptide antibiotics
👤 Balzarini, Jan 👤 Keyaerts, Els 👤 Vijgen, Leen 👤 Egberink, Herman 👤 De Clercq, Erik 👤 Van Ranst, Marc 👤 Printsevskaya, Svetlana S. 👤 Olsufyeva, Eugenia N. 👤 Solovieva, Svetlana E. 👤 Preobrazhenskaya, Maria N. ⏰ 2006 📚 Antiviral Research
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Pyridine N-oxide derivatives are inhibitory to the human SARS and feline infectious peritonitis coronavirus in cell culture
👤 Balzarini, Jan 👤 Keyaerts, Els 👤 Vijgen, Leen 👤 Vandermeer, Frank 👤 Stevens, Miguel 👤 De Clercq, Erik 👤 Egberink, Herman 👤 Van Ranst, Marc ⏰ 2006 📚 Journal of Antimicrobial Chemotherapy
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Molecular Pathogenesis of Middle East Respiratory Syndrome (MERS) Coronavirus
👤 Banerjee, Arinjay 👤 Baid, Kaushal 👤 Mossman, Karen ⏰ 2019 📚 Current Clinical Microbiology Reports
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Interferon regulatory factor 3-mediated signaling limits middle-east respiratory syndrome (MERS) coronavirus propagation in cells from an insectivorous bat
👤 Banerjee, Arinjay 👤 Falzarano, Darryl 👤 Rapin, Noreen 👤 Lew, Jocelyne 👤 Misra, Vikram ⏰ 2019 📚 Viruses
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Review of Emerging Pharmacotherapy for the Treatment of Coronavirus Disease 2019.
👤 Barlow, Ashley 👤 Landolf, Kaitlin M 👤 Barlow, Brooke 👤 Yeung, Siu Yan Amy 👤 Heavner, Jason J 👤 Claassen, Cassidy W 👤 Heavner, Mojdeh S ⏰ 2020 📚 Pharmacotherapy
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Inhibition of severe acute respiratory syndrome-associated coronavirus (SARSCoV) by calpain inhibitors and β-D-N4-hydroxycytidine
👤 Barnard, Dale L. 👤 Hubbard, Valerie D. 👤 Burton, Jared 👤 Smee, Donald F. 👤 Morrey, John D. 👤 Otto, Michael J. 👤 Sidwell, Robert W. ⏰ 2004 📚 Antiviral Chemistry and Chemotherapy
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Recent developments in anti-severe acute respiratory syndrome coronavirus chemotherapy
👤 Barnard, Dale L. 👤 Kumaki, Yohichi ⏰ 2011 📚 Future Virology
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A Comparative Review of Animal Models of Middle East Respiratory Syndrome Coronavirus Infection
👤 Baseler, L. 👤 de Wit, E. 👤 Feldmann, H. ⏰ 2016 📚 Veterinary Pathology
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Structural insights into the Middle East respiratory syndrome coronavirus 4a protein and its dsRNA binding mechanism
👤 Batool, Maria 👤 Shah, Masaud 👤 Patra, Mahesh Chandra 👤 Yesudhas, Dhanusha 👤 Choi, Sangdun ⏰ 2017 📚 Scientific Reports
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Mutagenesis of coronavirus nsp14 reveals its potential role in modulation of the innate immune response
👤 Becares, Martina 👤 Pascual-Iglesias, Alejandro 👤 Nogales, Aitor 👤 Sola, Isabel 👤 Enjuanes, Luis 👤 Zuñiga, Sonia ⏰ 2016 📚 Journal of Virology
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Overview of current therapeutics and novel candidates against influenza, respiratory syncytial virus, and Middle East respiratory syndrome coronavirus infections
👤 Behzadi, Mohammad Amin 👤 Leyva-Grado, Victor H. ⏰ 2019 📚 Frontiers in Microbiology
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PCR array profiling of antiviral genes in human embryonic kidney cells expressing human coronavirus OC43 structural and accessory proteins
👤 Beidas, Meshal 👤 Chehadeh, Wassim ⏰ 2018 📚 Archives of Virology
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PCR array profiling of antiviral genes in human embryonic kidney cells expressing human coronavirus OC43 structural and accessory proteins
👤 Beidas, Meshal 👤 Chehadeh, Wassim ⏰ 2018 📚 Archives of Virology
- Effect of Human Coronavirus OC43 Structural and Accessory Proteins on the Transcriptional Activation of Antiviral Response Elements
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Pathogenesis of murine coronavirus in the central nervous system
👤 Bender, Susan J. 👤 Weiss, Susan R. ⏰ 2010 📚 Journal of Neuroimmune Pharmacology
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The SARS-associated coronavirus - The first pandemic of the 21st century Das SARS-assoziierte coronavirus - Die erste pandemie des 21. Jahrhunderts
👤 Berger, Annemarie 👤 Drosten, Christian 👤 Doerr, Hans W. 👤 Preiser, Wolfgang ⏰ 2004 📚 LaboratoriumsMedizin
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Perforin and Gamma Interferon-Mediated Control of Coronavirus Central Nervous System Infection by CD8 T Cells in the Absence of CD4 T Cells
👤 Bergmann, Cornelia C. 👤 Parra, Beatriz 👤 Hinton, David R. 👤 Ramakrishna, Chandran 👤 Dowdell, Konechi C. 👤 Stohlman, Stephen A. ⏰ 2004 📚 Journal of Virology
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Tertiary structure prediction of SARS coronavirus helicase
👤 Bernini, Andrea 👤 Spiga, Ottavia 👤 Venditti, Vincenzo 👤 Prischi, Filippo 👤 Bracci, Luisa 👤 Huang, Jiandong 👤 Tanner, Julian A. 👤 Niccolai, Neri ⏰ 2006 📚 Biochemical and Biophysical Research Communications
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Potential broad spectrum inhibitors of the Coronavirus 3CLpro: A virtual screening and structure-based drug design study
👤 Berry, Michael 👤 Fielding, Burtram C. 👤 Gamieldien, Junaid ⏰ 2015 📚 Viruses
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TMPRSS2 activates the human coronavirus 229E for cathepsin-independent host cell entry and is expressed in viral target cells in the respiratory epithelium
👤 Bertram, Stephanie 👤 Dijkman, Ronald 👤 Habjan, Matthias 👤 Heurich, Adeline 👤 Gierer, Stefanie 👤 Glowacka, Ilona 👤 Welsch, Kathrin 👤 Winkler, Michael 👤 Schneider, Heike 👤 Hofmann-Winkler, Heike 👤 Volker Thiel, None 👤 Pöhlmann, Stefan ⏰ 2013 📚 Journal of Virology
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Cleavage and activation of the severe acute respiratory syndrome coronavirus spike protein by human airway trypsin-like protease
👤 Bertram, Stephanie 👤 Glowacka, Ilona 👤 Müller, Marcel A. 👤 Lavender, Hayley 👤 Gnirss, Kerstin 👤 Nehlmeier, Inga 👤 Niemeyer, Daniela 👤 He, Yuxian 👤 Simmons, Graham 👤 Drosten, Christian 👤 Soilleux, Elizabeth J. 👤 Jahn, Olaf 👤 Steffen, Imke 👤 Pöhlmann, Stefan ⏰ 2011 📚 Journal of Virology
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Activation of RNase L by murine coronavirus in myeloid cells is dependent on basal Oas gene expression and independent of virus-induced interferon
👤 Birdwell, L. Dillon 👤 Zalinger, Zachary B. 👤 Li, Yize 👤 Wright, Patrick W. 👤 Elliott, Ruth 👤 Rose, Kristine M. 👤 Silverman, Robert H. 👤 Weiss, Susan R. ⏰ 2016 📚 Journal of Virology
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Coronavirus escape from Heptad Repeat 2 (HR2)-derived peptide entry inhibition as a result of mutations in the HR1 domain of the spike fusion protein
👤 Bosch, Berend Jan 👤 Rossen, John W.A. 👤 Bartelink, Willem 👤 Zuurveen, Stephanie J. 👤 De Haan, Cornelis A.M. 👤 Duquerroy, Stephane 👤 Boucher, Charles A.B. 👤 Rottier, Peter J.M. ⏰ 2008 📚 Journal of Virology
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Coronavirus Nsp10, a critical co-factor for activation of multiple replicative enzymes
👤 Bouvet, Mickaël 👤 Lugari, Adrien 👤 Posthuma, Clara C. 👤 Zevenhoven, Jessika C. 👤 Bernard, Stéphanie 👤 Betzi, Stéphane 👤 Imbert, Isabelle 👤 Canard, Bruno 👤 Guillemot, Jean Claude 👤 Lécine, Patrick 👤 Pfefferle, Susanne 👤 Drosten, Christian 👤 Snijder, Eric J. 👤 Decroly, Etienne 👤 Morelli, Xavier ⏰ 2014 📚 Journal of Biological Chemistry
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Three amino acid changes in avian coronavirus spike protein allow binding to kidney tissue
👤 Bouwman, Kim M. 👤 Parsons, Lisa M. 👤 Berends, Alinda J. 👤 De Vries, Robert P. 👤 Cipollo, John F. 👤 Verheije, Monique H. ⏰ 2020 📚 Journal of Virology
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Broad spectrum antiviral remdesivir inhibits human endemic and zoonotic deltacoronaviruses with a highly divergent RNA dependent RNA polymerase
👤 Brown, Ariane J. 👤 Won, John J. 👤 Graham, Rachel L. 👤 Dinnon, Kenneth H. 👤 Sims, Amy C. 👤 Feng, Joy Y. 👤 Cihlar, Tomas 👤 Denison, Mark R. 👤 Baric, Ralph S. 👤 Sheahan, Timothy P. ⏰ 2019 📚 Antiviral Research
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ATP1A1-mediated Src signaling inhibits coronavirus entry into host cells
👤 Burkard, Christine 👤 Verheije, Monique H. 👤 Haagmans, Bart L. 👤 van Kuppeveld, Frank J. 👤 Rottier, Peter J.M. 👤 Bosch, Berend Jan 👤 de Haan, Cornelis A.M. ⏰ 2015 📚 Journal of Virology
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Antiviral effects of antisense morpholino oligomers in murine coronavirus infection models
👤 Burrer, Renaud 👤 Neuman, Benjamin W. 👤 Ting, Joey P.C. 👤 Stein, David A. 👤 Moulton, Hong M. 👤 Iversen, Patrick L. 👤 Kuhn, Peter 👤 Buchmeier, Michael J. ⏰ 2007 📚 Journal of Virology
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Myd88 Initiates Early Innate Immune Responses and Promotes CD4 T Cells during Coronavirus Encephalomyelitis
👤 Butchi, Niranjan 👤 Kapil, Parul 👤 Puntambekar, Shweta 👤 Stohlman, Stephen A. 👤 Hinton, David R. 👤 Bergmann, Cornelia C. ⏰ 2015 📚 Journal of Virology
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Ifit2 deficiency results in uncontrolled neurotropic coronavirus replication and enhanced encephalitis via impaired alpha/beta interferon induction in macrophages
👤 Butchi, Niranjan B. 👤 Hinton, David R. 👤 Stohlman, Stephen A. 👤 Kapil, Parul 👤 Fensterl, Volker 👤 Sen, Ganes C. 👤 Bergmann, Cornelia C. ⏰ 2014 📚 Journal of Virology
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Antiviral antibodies are necessary to prevent cytotoxic T-lymphocyte escape in mice infected with a coronavirus
👤 Butler, Noah S. 👤 Dandekar, Ajai A. 👤 Perlman, Stanley ⏰ 2007 📚 Journal of Virology
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X-ray structural and biological evaluation of a series of potent and highly selective inhibitors of human coronavirus papain-like proteases
👤 Báez-Santos, Yahira M. 👤 Barraza, Scott J. 👤 Wilson, Michael W. 👤 Agius, Michael P. 👤 Mielech, Anna M. 👤 Davis, Nicole M. 👤 Baker, Susan C. 👤 Larsen, Scott D. 👤 Mesecar, Andrew D. ⏰ 2014 📚 Journal of Medicinal Chemistry
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The SARS-coronavirus papain-like protease: Structure, function and inhibition by designed antiviral compounds
👤 Báez-Santos, Yahira M. 👤 St. John, Sarah E. 👤 Mesecar, Andrew D. ⏰ 2015 📚 Antiviral Research
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The SARS-coronavirus papain-like protease: Structure, function and inhibition by designed antiviral compounds
👤 Báez-Santos, Yahira M. 👤 St. John, Sarah E. 👤 Mesecar, Andrew D. ⏰ 2015 📚 Antiviral Research
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Computational inference of selection underlying the evolution of the novel coronavirus, SARS-CoV-2.
👤 Cagliani, Rachele 👤 Forni, Diego 👤 Clerici, Mario 👤 Sironi, Manuela ⏰ 2020 📚 J Virol
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Down-regulation of transcription of the proapoptotic gene BNip3 in cultured astrocytes by murine coronavirus infection
👤 Cai, Yingyun 👤 Liu, Yin 👤 Yu, Dongdong 👤 Zhang, Xuming ⏰ 2003 📚 Virology
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Isolation and rapid sharing of the 2019 novel coronavirus (SARS-CoV-2) from the first patient diagnosed with COVID-19 in Australia.
👤 Caly, Leon 👤 Druce, Julian 👤 Roberts, Jason 👤 Bond, Katherine 👤 Tran, Thomas 👤 Kostecki, Renata 👤 Yoga, Yano 👤 Naughton, William 👤 Taiaroa, George 👤 Seemann, Torsten 👤 Schultz, Mark B 👤 Howden, Benjamin P 👤 Korman, Tony M 👤 Lewin, Sharon R 👤 Williamson, Deborah A 👤 Catton, Mike G ⏰ 2020 📚 Med J Aust
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Lack of Innate Interferon Responses during SARS Coronavirus Infection in a Vaccination and Reinfection Ferret Model
👤 Cameron, Mark J. 👤 Kelvin, Alyson A. 👤 Leon, Alberto J. 👤 Cameron, Cheryl M. 👤 Ran, Longsi 👤 Xu, Luoling 👤 Chu, Yong Kyu 👤 Danesh, Ali 👤 Fang, Yuan 👤 Li, Qianjun 👤 Anderson, Austin 👤 Couch, Ronald C. 👤 Paquette, Stephane G. 👤 Fomukong, Ndingsa G. 👤 Kistner, Otfried 👤 Lauchart, Manfred 👤 Rowe, Thomas 👤 Harrod, Kevin S. 👤 Jonsson, Colleen B. 👤 Kelvin, David J. ⏰ 2012 📚 PLoS ONE
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A screen of the NIH Clinical Collection small molecule library identifies potential anti-coronavirus drugs
👤 Cao, Jianzhong 👤 Forrest, J. Craig 👤 Zhang, Xuming ⏰ 2015 📚 Antiviral Research
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Role of severe acute respiratory syndrome coronavirus viroporins E, 3a, and 8a in replication and pathogenesis
👤 Castaño-Rodriguez, Carlos 👤 Honrubia, Jose M. 👤 Gutiérrez-Álvarez, Javier 👤 DeDiego, Marta L. 👤 Nieto-Torres, Jose L. 👤 Jimenez-Guardeño, Jose M. 👤 Regla-Nava, Jose A. 👤 Fernandez-Delgado, Raul 👤 Verdia-Báguena, Carmina 👤 Queralt-Martín, Maria 👤 Kochan, Grazyna 👤 Perlman, Stanley 👤 Aguilella, Vicente M. 👤 Sola, Isabel 👤 Enjuanes, Luis ⏰ 2018 📚 mBio
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Genomic variance of the 2019-nCoV coronavirus.
👤 Ceraolo, Carmine 👤 Giorgi, Federico M ⏰ 2020 📚 J Med Virol
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Recommendations for coronavirus infection in rheumatic diseases treated with biologic therapy.
👤 Ceribelli, Angela 👤 Motta, Francesca 👤 De Santis, Maria 👤 Ansari, Aftab A 👤 Ridgway, William M 👤 Gershwin, M Eric 👤 Selmi, Carlo ⏰ 2020 📚 J Autoimmun
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Dendritic cell-specific antigen delivery by coronavirus vaccine vectors induces long-lasting protective antiviral and antitumor immunity
👤 Cervantes-Barragan, Luisa 👤 Züst, Roland 👤 Maier, Reinhard 👤 Sierro, Sophie 👤 Janda, Jozef 👤 Levy, Frederic 👤 Speiser, Daniel 👤 Romero, Pedro 👤 Rohrlich, Pierre Simon 👤 Ludewig, Burkhard 👤 Thiel, Volker ⏰ 2010 📚 mBio
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Broad-spectrum antivirals for the emerging Middle East respiratory syndrome coronavirus
👤 Chan, Jasper F.W. 👤 Chan, Kwok Hung 👤 Kao, Richard Y.T. 👤 To, Kelvin K.W. 👤 Zheng, Bo Jian 👤 Li, Clara P.Y. 👤 Li, Patrick T.W. 👤 Dai, Jun 👤 Mok, Florence K.Y. 👤 Chen, Honglin 👤 Hayden, Frederick G. 👤 Yuen, Kwok Yung ⏰ 2013 📚 Journal of Infection
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Middle East Respiratory syndrome coronavirus: Another zoonotic betacoronavirus causing SARS-like disease
👤 Chan, Jasper F.W. 👤 Lau, Susanna K.P. 👤 To, Kelvin K.W. 👤 Cheng, Vincent C.C. 👤 Woo, Patrick C.Y. 👤 Yue, Kwok Yung ⏰ 2015 📚 Clinical Microbiology Reviews
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Middle East Respiratory syndrome coronavirus: Another zoonotic betacoronavirus causing SARS-like disease
👤 Chan, Jasper F.W. 👤 Lau, Susanna K.P. 👤 To, Kelvin K.W. 👤 Cheng, Vincent C.C. 👤 Woo, Patrick C.Y. 👤 Yue, Kwok Yung ⏰ 2015 📚 Clinical Microbiology Reviews
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The emerging novel Middle East respiratory syndrome coronavirus: The "knowns" and "unknowns"
👤 Chan, Jasper Fuk Woo 👤 Lau, Susanna Kar Pui 👤 Woo, Patrick Chiu Yat ⏰ 2013 📚 Journal of the Formosan Medical Association
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Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan.
👤 Chan, Jasper Fuk-Woo 👤 Kok, Kin-Hang 👤 Zhu, Zheng 👤 Chu, Hin 👤 To, Kelvin Kai-Wang 👤 Yuan, Shuofeng 👤 Yuen, Kwok-Yung ⏰ 2020 📚 Emerg Microbes Infect
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The SARS coronavirus nucleocapsid protein - Forms and functions
👤 Chang, Chung Ke 👤 Hou, Ming Hon 👤 Chang, Chi Fon 👤 Hsiao, Chwan Deng 👤 Huang, Tai Huang ⏰ 2014 📚 Antiviral Research
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Structure-based virtual screening and experimental validation of the discovery of inhibitors targeted towards the human coronavirus nucleocapsid protein
👤 Chang, Chung Ke 👤 Jeyachandran, Sivakamavalli 👤 Hu, Nien Jen 👤 Liu, Chia Ling 👤 Lin, Shing Yen 👤 Wang, Yong Sheng 👤 Chang, Yu Ming 👤 Hou, Ming Hon ⏰ 2016 📚 Molecular BioSystems
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Inhibition of transmissible gastroenteritis coronavirus (TGEV) multiplication in vitro by non-immune lymphocytes Inhibition de la multiplication in vitro du coronavirus de la gastroentérite transmissible (GET) par des lymphocytes non immuns
👤 Charley, B. 👤 Laude, H. 👤 La Bonnardière, C. ⏰ 1987 📚 Annales de l'Institut Pasteur Virology
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Toona sinensis Roem tender leaf extract inhibits SARS coronavirus replication
👤 Chen, Chung Jen 👤 Michaelis, Martin 👤 Hsu, Hseng Kuang 👤 Tsai, Chin Chuan 👤 Yang, Kunder D. 👤 Wu, Yang Chang 👤 Cinatl Jr., Jindrich 👤 Doerr, Hans Wilhelm ⏰ 2008 📚 Journal of Ethnopharmacology
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In vitro susceptibility of 10 clinical isolates of SARS coronavirus to selected antiviral compounds
👤 Chen, F. 👤 Chan, K. H. 👤 Jiang, Y. 👤 Kao, R. Y.T. 👤 Lu, H. T. 👤 Fan, K. W. 👤 Cheng, V. C.C. 👤 Tsui, W. H.W. 👤 Hung, I. F.N. 👤 Lee, T. S.W. 👤 Guan, Y. 👤 Peiris, J. S.M. 👤 Yuen, K. Y. ⏰ 2004 📚 Journal of Clinical Virology
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In vitro susceptibility of 10 clinical isolates of SARS coronavirus to selected antiviral compounds
👤 Chen, F. 👤 Chan, K. H. 👤 Jiang, Y. 👤 Kao, R. Y.T. 👤 Lu, H. T. 👤 Fan, K. W. 👤 Cheng, V. C.C. 👤 Tsui, W. H.W. 👤 Hung, I. F.N. 👤 Lee, T. S.W. 👤 Guan, Y. 👤 Peiris, J. S.M. 👤 Yuen, K. Y. ⏰ 2004 📚 Journal of Clinical Virology
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Synthetic virus-like particles prepared via protein corona formation enable effective vaccination in an avian model of coronavirus infection
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Cinanserin is an inhibitor of the 3C-like proteinase of severe acute respiratory syndrome coronavirus and strongly reduces virus replication in vitro
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Coronavirus membrane-associated papain-like proteases induce autophagy through interacting with Beclin1 to negatively regulate antiviral innate immunity
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SARS coronavirus papain-like protease inhibits the type I interferon signaling pathway through interaction with the STING-TRAF3-TBK1 complex
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Functional screen reveals SARS coronavirus nonstructural protein nsp14 as a novel cap N7 methyltransferase
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Prediction of the SARS-CoV-2 (2019-nCoV) 3C-like protease (3CL (pro)) structure: virtual screening reveals velpatasvir, ledipasvir, and other drug repurposing candidates.
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Antigenicity analysis of different regions of the severe acute respiratory syndrome coronavirus nucleocapsid protein
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Proteolytic processing and deubiquitinating activity of papain-like proteases of human coronavirus NL63
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Thiopurine analogs and mycophenolic acid synergistically inhibit the papain-like protease of Middle East respiratory syndrome coronavirus
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Antiviral effects of saikosaponins on human coronavirus 229E in vitro
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Significance of the Myxovirus resistance A (MxA) gene - 123C>A single-nucleotide polymorphism in suppressed interferon ß induction of severe acute respiratory syndrome coronavirus infection
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Thiopurine analogues inhibit papain-like protease of severe acute respiratory syndrome coronavirus
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Remdesivir, lopinavir, emetine, and homoharringtonine inhibit SARS-CoV-2 replication in vitro.
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Antiviral activity of nucleoside analogues against SARS-coronavirus (SARS-CoV)
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Biopolymeric nano/microspheres for selective and reversible adsorption of coronaviruses
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Glycyrrhizin, an active component of liquorice roots, and replication of SARS-associated coronavirus
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In vitro studies on the use of clay, clay minerals and charcoal to adsorb bovine rotavirus and bovine coronavirus
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Antagonism of dsRNA-induced innate immune pathways by NS4a and NS4b accessory proteins during MERS coronavirus infection
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Transcriptome analysis of chicken kidney tissues following coronavirus avian infectious bronchitis virus infection
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Nucleocapsid protein recruitment to replication-transcription complexes plays a crucial role in coronaviral life cycle
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Prophylactic and postexposure efficacy of a potent human monoclonal antibody against MERS coronavirus
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The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade.
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Alphacoronavirus protein 7 modulates host innate immune response
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Coronavirus gene 7 counteracts host defenses and modulates virus virulence
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The nucleocapsid protein of coronaviruses acts as a viral suppressor of RNA silencing in mammalian cells
👤 Cui, Lei 👤 Wang, Haiying 👤 Ji, Yanxi 👤 Yang, Jie 👤 Xu, Shan 👤 Huang, Xingyu 👤 Wang, Zidao 👤 Qin, Lei 👤 Tien, Po 👤 Zhou, Xi 👤 Guo, Deyin 👤 Chen, Yu ⏰ 2015 📚 Journal of Virology
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Early gene expression events in ferrets in response to SARS coronavirus infection versus direct interferon-alpha2b stimulation
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Coronavirus Disease 2019 (COVID-19) Pandemic and Pregnancy.
👤 Dashraath, Pradip 👤 Jing Lin Jeslyn, Wong 👤 Mei Xian Karen, Lim 👤 Li Min, Lim 👤 Sarah, Li 👤 Biswas, Arijit 👤 Arjandas Choolani, Mahesh 👤 Mattar, Citra 👤 Lin, Su Lin ⏰ 2020 📚 Am J Obstet Gynecol
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Potential antivirals and antiviral strategies against SARS coronavirus infections
👤 De Clercq, Erik ⏰ 2006 📚 Expert Review of Anti-Infective Therapy
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Natural history of a recurrent feline coronavirus infection and the role of cellular immunity in survival and disease
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Interferon-γ and interleukin-4 downregulate expression of the SARS coronavirus receptor ACE2 in Vero E6 cells
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Alisporivir inhibits MERS- and SARS-coronavirus replication in cell culture, but not SARS-coronavirus infection in a mouse model
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MERS-coronavirus replication induces severe in vitro cytopathology and is strongly inhibited by cyclosporin A or interferon-α treatment
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A kinome-wide small interfering RNA screen identifies proviral and antiviral host factors in severe acute respiratory syndrome coronavirus replication, including double-stranded RNA-activated protein kinase and early secretory pathway proteins
👤 de Wilde, Adriaan H. 👤 Wannee, Kazimier F. 👤 Scholte, Florine E.M. 👤 Goeman, Jelle J. 👤 Ten Dijke, Peter 👤 Snijder, Eric J. 👤 Kikkert, Marjolein 👤 van Hemert, Martijn J. ⏰ 2015 📚 Journal of Virology
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Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.
👤 de Wit, Emmie 👤 Feldmann, Friederike 👤 Cronin, Jacqueline 👤 Jordan, Robert 👤 Okumura, Atsushi 👤 Thomas, Tina 👤 Scott, Dana 👤 Cihlar, Tomas 👤 Feldmann, Heinz ⏰ 2020 📚 Proc Natl Acad Sci U S A
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Inhibition of NF-κB-mediated inflammation in severe acute respiratory syndrome coronavirus-infected mice increases survival
👤 DeDiego, Marta L. 👤 Nieto-Torres, Jose L. 👤 Regla-Nava, Jose A. 👤 Jimenez-Guardeño, Jose M. 👤 Fernandez-Delgado, Raul 👤 Fett, Craig 👤 Castaño-Rodriguez, Carlos 👤 Perlman, Stanley 👤 Enjuanes, Luis ⏰ 2014 📚 Journal of Virology
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The antiviral action of common household disinfectants and antiseptics against murine hepatitis virus, a potential surrogate for SARS coronavirus
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Regulation of IRF-3-dependent innate immunity by the papain-like protease domain of the severe acute respiratory syndrome coronavirus
👤 Devaraj, Santhana G. 👤 Wang, Nan 👤 Chen, Zhongbin 👤 Chen, Zihong 👤 Tseng, Monica 👤 Barretto, Naina 👤 Lin, Rongtuan 👤 Peters, Clarence J. 👤 Tseng, Chien Te K. 👤 Baker, Susan C. 👤 Li, Kui ⏰ 2007 📚 Journal of Biological Chemistry
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COVID-19, an emerging coronavirus infection: advances and prospects in designing and developing vaccines, immunotherapeutics, and therapeutics.
👤 Dhama, Kuldeep 👤 Sharun, Khan 👤 Tiwari, Ruchi 👤 Dadar, Maryam 👤 Malik, Yashpal Singh 👤 Singh, Karam Pal 👤 Chaicumpa, Wanpen ⏰ 2020 📚 Hum Vaccin Immunother
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MicroRNA-155 enhances T cell trafficking and antiviral effector function in a model of coronavirus-induced neurologic disease
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The clinical characteristics of pneumonia patients coinfected with 2019 novel coronavirus and influenza virus in Wuhan, China.
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Discovering drugs to treat coronavirus disease 2019 (COVID-19).
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A guideline for homology modeling of the proteins from newly discovered betacoronavirus, 2019 novel coronavirus (2019-nCoV).
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SARS coronavirus spike protein-induced innate immune response occurs via activation of the NF-κB pathway in human monocyte macrophages in vitro
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Glutathione-Capped Ag2S Nanoclusters Inhibit Coronavirus Proliferation through Blockage of Viral RNA Synthesis and Budding
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Favipiravir: pharmacokinetics and concerns about clinical trials for 2019-nCoV infection.
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Clinical Features of 85 Fatal Cases of COVID-19 from Wuhan: A Retrospective Observational Study.
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Tilorone: a Broad-Spectrum Antiviral Invented in the USA and Commercialized in Russia and beyond.
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Tilorone: A Broad-Spectrum Antiviral For Emerging Viruses.
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Ribavirin, Remdesivir, Sofosbuvir, Galidesivir, and Tenofovir against SARS-CoV-2 RNA dependent RNA polymerase (RdRp): A molecular docking study.
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Analysis of the Host Transcriptome from Demyelinating Spinal Cord of Murine Coronavirus-Infected Mice
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Identification of a broad-spectrum antiviral small molecule against severe acute respiratory syndrome coronavirus and Ebola, Hendra, And Nipah viruses by using a novel high-throughput screening assay
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Protection from SARS coronavirus conferred by live measles vaccine expressing the spike glycoprotein
👤 Escriou, Nicolas 👤 Callendret, Benoît 👤 Lorin, Valérie 👤 Combredet, Chantal 👤 Marianneau, Philippe 👤 Février, Michèle 👤 Tangy, Frédéric ⏰ 2014 📚 Virology
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Repurposing of clinically approved drugs for treatment of coronavirus disease 2019 in a 2019-novel coronavirus (2019-nCoV) related coronavirus model.
👤 Fan, Hua-Hao 👤 Wang, Li-Qin 👤 Liu, Wen-Li 👤 An, Xiao-Ping 👤 Liu, Zhen-Dong 👤 He, Xiao-Qi 👤 Song, Li-Hua 👤 Tong, Yi-Gang ⏰ 2020 📚 Chin Med J (Engl)
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Porcine deltacoronavirus accessory protein NS6 antagonizes interferon beta production by interfering with the binding of RIG-I/MDA5 to double-stranded RNA
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The conserved coronavirus macrodomain promotes virulence and suppresses the innate immune response during severe acute respiratory syndrome coronavirus infection
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Structural and molecular basis of mismatch correction and ribavirin excision from coronavirus RNA
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The heptad repeat region is a major selection target in MERS-CoV and related coronaviruses
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Synthesis and Biological Evaluation of Novel (thio)semicarbazone-Based Benzimidazoles as Antiviral Agents against Human Respiratory Viruses.
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Molecular determinants for subcellular localization of the severe acute respiratory syndrome coronavirus open reading frame 3b protein
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Severe acute respiratory syndrome coronavirus ORF6 antagonizes STAT1 function by sequestering nuclear import factors on the rough endoplasmic reticulum/Golgi membrane
👤 Frieman, Matthew 👤 Yount, Boyd 👤 Heise, Mark 👤 Kopecky-Bromberg, Sarah A. 👤 Palese, Peter 👤 Baric, Ralph S. ⏰ 2007 📚 Journal of Virology
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Preparation and evaluation of anti-SARS coronavirus IgY from yolks of immunized SPF chickens
👤 Fu, Chao Yang 👤 Huang, He 👤 Wang, Xiao Mei 👤 Liu, Yong Gang 👤 Wang, Zhi Guo 👤 Cui, Shang Jin 👤 Gao, Hong Lei 👤 Li, Zan 👤 Li, Jing Peng 👤 Kong, Xian Gang ⏰ 2006 📚 Journal of Virological Methods
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Understanding SARS-CoV-2-Mediated Inflammatory Responses: From Mechanisms to Potential Therapeutic Tools.
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A tug-of-war between severe acute respiratory syndrome coronavirus 2 and host antiviral defence: lessons from other pathogenic viruses.
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Discovery, synthesis, and structure-based optimization of a series of N -(tert -Butyl)-2-(N -arylamido)-2-(pyridin-3-yl) acetamides (ML188) as potent noncovalent small molecule inhibitors of the severe acute respiratory syndrome coronavirus (SARS-CoV) 3CL protease
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Synthesis, biological evaluation and molecular modeling of a novel series of fused 1,2,3-triazoles as potential anti-coronavirus agents
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The ORF4b-encoded accessory proteins of Middle East respiratory syndrome coronavirus and two related bat coronaviruses localize to the nucleus and inhibit innate immune signalling
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Protective role of toll-like receptor 3-induced type I interferon in murine coronavirus infection of macrophages
👤 Mazaleuskaya, Liudmila 👤 Veltrop, Rogier 👤 Ikpeze, Nneka 👤 Martin-Garcia, Julio 👤 Navas-Martin, Sonia ⏰ 2012 📚 Viruses
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Lethal infection of K18-hACE2 mice infected with severe acute respiratory syndrome coronavirus
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In vitro inhibition of feline coronavirus replication by small interfering RNAs
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Identification and characterisation of small molecule inhibitors of feline coronavirus replication
👤 McDonagh, Phillip 👤 Sheehy, Paul A. 👤 Norris, Jacqueline M. ⏰ 2014 📚 Veterinary Microbiology
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Combination siRNA therapy against feline coronavirus can delay the emergence of antiviral resistance in vitro
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A review of genetic methods and models for analysis of coronavirus-induced severe pneumonitis
👤 McGruder, Brenna 👤 Leibowitz, Julian L. ⏰ 2015 📚 Journal of General Virology
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Pathogenic influenza viruses and coronaviruses utilize similar and contrasting approaches to control interferon-stimulated gene responses
👤 Menachery, Vineet D. 👤 Eisfeld, Amie J. 👤 Schäfer, Alexandra 👤 Josset, Laurence 👤 Sims, Amy C. 👤 Proll, Sean 👤 Fan, Shufang 👤 Li, Chengjun 👤 Neumann, Gabriele 👤 Tilton, Susan C. 👤 Chang, Jean 👤 Gralinski, Lisa E. 👤 Long, Casey 👤 Green, Richard 👤 Williams, Christopher M. 👤 Weiss, Jeffrey 👤 Matzke, Melissa M. 👤 Webb-Robertson, Bobbie Jo 👤 Schepmoes, Athena A. 👤 Shukla, Anil K. 👤 Metz, Thomas O. 👤 Smith, Richard D. 👤 Waters, Katrina M. 👤 Katze, Michael G. 👤 Kawaoka, Yoshihiro 👤 Baric, Ralph S. ⏰ 2014 📚 mBio
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Middle East respiratory syndrome coronavirus infection is inhibited by griffithsin
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Clinical characteristics of refractory COVID-19 pneumonia in Wuhan, China.
👤 Mo, Pingzheng 👤 Xing, Yuanyuan 👤 Xiao, Yu 👤 Deng, Liping 👤 Zhao, Qiu 👤 Wang, Hongling 👤 Xiong, Yong 👤 Cheng, Zhenshun 👤 Gao, Shicheng 👤 Liang, Ke 👤 Luo, Mingqi 👤 Chen, Tielong 👤 Song, Shihui 👤 Ma, Zhiyong 👤 Chen, Xiaoping 👤 Zheng, Ruiying 👤 Cao, Qian 👤 Wang, Fan 👤 Zhang, Yongxi ⏰ 2020 📚 Clin Infect Dis
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Transmissible gastroenteritis coronavirus genome packaging signal is located at the 5' end of the genome and promotes viral RNA incorporation into virions in a replication-independent process
👤 Morales, Lucia 👤 Mateos-Gomez, Pedro A. 👤 Capiscol, Carmen 👤 del Palacio, Lorena 👤 Enjuanes, Luis 👤 Sola, Isabel ⏰ 2013 📚 Journal of Virology
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The expression and antigenicity of a truncated spike-nucleocapsid fusion protein of severe acute respiratory syndrome-associated coronavirus
👤 Mu, Feng 👤 Niu, Dongsheng 👤 Mu, Jingsong 👤 He, Bo 👤 Han, Weiguo 👤 Fan, Baoxing 👤 Huang, Shengyong 👤 Qiu, Yan 👤 You, Bo 👤 Chen, Weijun ⏰ 2008 📚 BMC Microbiology
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Transgene expression in the genome of middle east respiratory syndrome coronavirus based on a novel reverse genetics system utilizing red-mediated recombination cloning
👤 Muth, Doreen 👤 Meyer, Benjamin 👤 Niemeyer, Daniela 👤 Schroeder, Simon 👤 Osterrieder, Nikolaus 👤 Müller, Marcel Alexander 👤 Drosten, Christian ⏰ 2017 📚 Journal of General Virology
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A synthetic consensus anti-spike protein DNA vaccine induces protective immunity against Middle East respiratory syndrome coronavirus in nonhuman primates
👤 Muthumani, Karuppiah 👤 Falzarano, Darryl 👤 Reuschel, Emma L. 👤 Tingey, Colleen 👤 Flingai, Seleeke 👤 Villarreal, Daniel O. 👤 Wise, Megan 👤 Patel, Ami 👤 Izmirly, Abdullah 👤 Aljuaid, Abdulelah 👤 Seliga, Alecia M. 👤 Soule, Geoff 👤 Morrow, Matthew 👤 Kraynyak, Kimberly A. 👤 Khan, Amir S. 👤 Scott, Dana P. 👤 Feldmann, Friederike 👤 LaCasse, Rachel 👤 Meade-White, Kimberly 👤 Okumura, Atsushi 👤 Ugen, Kenneth E. 👤 Sardesai, Niranjan Y. 👤 Kim, J. Joseph 👤 Kobinger, Gary 👤 Feldmann, Heinz 👤 Weiner, David B. ⏰ 2015 📚 Science Translational Medicine
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Inhibition of cytosolic phospholipase A2α impairs an early step of coronavirus replication in cell culture
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Inhibition of stress granule formation by middle east respiratory syndrome coronavirus 4a accessory protein facilitates viral translation, leading to efficient virus replication
👤 Nakagawa, Keisuke 👤 Narayanan, Krishna 👤 Wada, Masami 👤 Makino, Shinji ⏰ 2018 📚 Journal of Virology
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Coronavirus nonstructural protein 1: Common and distinct functions in the regulation of host and viral gene expression
👤 Narayanan, Krishna 👤 Ramirez, Sydney I. 👤 Lokugamage, Kumari G. 👤 Makino, Shinji ⏰ 2015 📚 Virus Research
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Inhibition, escape, and attenuated growth of severe acute respiratory syndrome coronavirus treated with antisense morpholino oligomers
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Antisense morpholino-oligomers directed against the 5′ end of the genome inhibit coronavirus proliferation and growth
👤 Neuman, Benjamin W. 👤 Stein, David A. 👤 Kroeker, Andrew D. 👤 Paulino, Amy D. 👤 Moulton, Hong M. 👤 Iversen, Patrick L. 👤 Buchmeier, Michael J. ⏰ 2004 📚 Journal of Virology
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Human papillomavirus type 16 E7 peptide-directed CD8+ T cells from patients with cervical cancer are cross-reactive with the coronavirus NS2 protein
👤 Nilges, Katja 👤 Höhn, Hanni 👤 Pilch, Henryk 👤 Neukirch, Claudia 👤 Freitag, Kirsten 👤 Talbot, P. J. 👤 Maeurer, Markus J. ⏰ 2003 📚 Journal of Virology
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Design of Potential RNAi (miRNA and siRNA) Molecules for Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Gene Silencing by Computational Method
👤 Nur, Suza Mohammad 👤 Hasan, Md Anayet 👤 Amin, Mohammad Al 👤 Hossain, Mehjabeen 👤 Sharmin, Tahmina ⏰ 2015 📚 Interdisciplinary Sciences: Computational Life Sciences
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Broad-spectrum in vitro activity and in vivo efficacy of the antiviral protein griffithsin against emerging viruses of the family Coronaviridae
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Design of an epitope-based peptide vaccine against spike protein of human coronavirus: An in silico approach
👤 Oany, Arafat Rahman 👤 Emran, Abdullah Al 👤 Jyoti, Tahmina Pervin ⏰ 2014 📚 Drug Design, Development and Therapy
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Ribavirin and interferon alfa-2a for severe Middle East respiratory syndrome coronavirus infection: A retrospective cohort study
👤 Omrani, Ali S. 👤 Saad, Mustafa M. 👤 Baig, Kamran 👤 Bahloul, Abdelkarim 👤 Abdul-Matin, Mohammed 👤 Alaidaroos, Amal Y. 👤 Almakhlafi, Ghaleb A. 👤 Albarrak, Mohammed M. 👤 Memish, Ziad A. 👤 Albarrak, Ali M. ⏰ 2014 📚 The Lancet Infectious Diseases
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Unrevealing sequence and structural features of novel coronavirus using in silico approaches: The main protease as molecular target.
👤 Ortega, Joseph Thomas 👤 Serrano, Maria Luisa 👤 Pujol, Flor Helene 👤 Rangel, Hector Rafael ⏰ 2020 📚 EXCLI J
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New antiviral drugs, vaccines and classic public health interventions against SARS coronavirus
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Potential Rapid Diagnostics, Vaccine and Therapeutics for 2019 Novel Coronavirus (2019-nCoV): A Systematic Review.
👤 Pang, Junxiong 👤 Wang, Min Xian 👤 Ang, Ian Yi Han 👤 Tan, Sharon Hui Xuan 👤 Lewis, Ruth Frances 👤 Chen, Jacinta I-Pei 👤 Gutierrez, Ramona A 👤 Gwee, Sylvia Xiao Wei 👤 Chua, Pearleen Ee Yong 👤 Yang, Qian 👤 Ng, Xian Yi 👤 Yap, Rowena Ks 👤 Tan, Hao Yi 👤 Teo, Yik Ying 👤 Tan, Chorh Chuan 👤 Cook, Alex R 👤 Yap, Jason Chin-Huat 👤 Hsu, Li Yang ⏰ 2020 📚 J Clin Med
- Atypical pneumonia caused by coronavirus Pneumopathies dites atypiques à coronavirus
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Synthesis and antiviral evaluation of 7-O-arylmethylquercetin derivatives against SARS-associated coronavirus (SCV) and hepatitis C virus (HCV)
👤 Park, Hye Ri 👤 Yoon, Hyunjun 👤 Kim, Mi Kyoung 👤 Lee, Sung Dae 👤 Chong, Youhoon ⏰ 2012 📚 Archives of Pharmacal Research
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First Pediatric Case of Coronavirus Disease 2019 in Korea.
👤 Park, Ji Young 👤 Han, Mi Seon 👤 Park, Kyoung Un 👤 Kim, Ji Young 👤 Choi, Eun Hwa ⏰ 2020 📚 J Korean Med Sci
- Lipidation increases antiviral activities of coronavirus fusion-inhibiting peptides
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Identification of rna pseudoknot-binding ligand that inhibits the - 1 ribosomal frameshifting of SARS-coronavirus by structure-based virtual screening
👤 Park, So Jung 👤 Kim, Yang Gyun 👤 Park, Hyun Ju ⏰ 2011 📚 Journal of the American Chemical Society
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Protease inhibitors broadly effective against feline, ferret and mink coronaviruses
👤 Perera, Krishani Dinali 👤 Galasiti Kankanamalage, Anushka C. 👤 Rathnayake, Athri D. 👤 Honeyfield, Amanda 👤 Groutas, William 👤 Chang, Kyeong Ok 👤 Kim, Yunjeong ⏰ 2018 📚 Antiviral Research
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Characterization of amino acid substitutions in feline coronavirus 3C-like protease from a cat with feline infectious peritonitis treated with a protease inhibitor
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Design, synthesis and evaluation of a series of acyclic fleximer nucleoside analogues with anti-coronavirus activity
👤 Peters, Hannah L. 👤 Jochmans, Dirk 👤 De Wilde, Adriaan H. 👤 Posthuma, Clara C. 👤 Snijder, Eric J. 👤 Neyts, Johan 👤 Seley-Radtke, Katherine L. ⏰ 2015 📚 Bioorganic and Medicinal Chemistry Letters
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The SARS-Coronavirus-host interactome: Identification of cyclophilins as target for pan-Coronavirus inhibitors
👤 Pfefferle, Susanne 👤 Schöpf, Julia 👤 Kögl, Manfred 👤 Friedel, Caroline C. 👤 Müller, Marcel A. 👤 Carbajo-Lozoya, Javier 👤 Stellberger, Thorsten 👤 von Dall'Armi, Ekatarina 👤 Herzog, Petra 👤 Kallies, Stefan 👤 Niemeyer, Daniela 👤 Ditt, Vanessa 👤 Kuri, Thomas 👤 Züst, Roland 👤 Pumpor, Ksenia 👤 Hilgenfeld, Rolf 👤 Schwarz, Frank 👤 Zimmer, Ralf 👤 Steffen, Imke 👤 Weber, Friedemann 👤 Thiel, Volker 👤 Herrler, Georg 👤 Thiel, Heinz Jürgen 👤 Schwegmann-Weßels, Christel 👤 Pöhlmann, Stefan 👤 Haas, Jürgen 👤 Drosten, Christian 👤 von Brunn, Albrecht ⏰ 2011 📚 PLoS Pathogens
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A three-stemmed mRNA pseudoknot in the SARS coronavirus frameshift signal
👤 Plant, Ewan P. 👤 Pérez-Alvarado, Gabriela C. 👤 Jacobs, Jonathan L. 👤 Mukhopadhyay, Bani 👤 Hennig, Mirko 👤 Dinman, Jonathan D. ⏰ 2005 📚 PLoS Biology
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Role of the lipid rafts in the life cycle of canine coronavirus
👤 Pratelli, Annamaria 👤 Colao, Valeriana ⏰ 2015 📚 Journal of General Virology
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Quantification of mRNA encoding cytokines and chemokines and assessment of ciliary function in canine tracheal epithelium during infection with canine respiratory coronavirus (CRCoV)
👤 Priestnall, Simon L. 👤 Mitchell, Judy A. 👤 Brooks, Harriet W. 👤 Brownlie, Joe 👤 Erles, Kerstin ⏰ 2009 📚 Veterinary Immunology and Immunopathology
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Nucleoside analogues for the treatment of coronavirus infections
👤 Pruijssers, Andrea J. 👤 Denison, Mark R. ⏰ 2019 📚 Current Opinion in Virology
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Inhibition of human coronavirus NL63 infection at early stages of the replication cycle
👤 Pyrc, Krzysztof 👤 Bosch, Berend Jan 👤 Berkhout, Ben 👤 Jebbink, Maarten F. 👤 Dijkman, Ronald 👤 Rottier, Peter 👤 Van Der Hoek, Lia ⏰ 2006 📚 Antimicrobial Agents and Chemotherapy
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The proteasome inhibitor velcade enhances rather than reduces disease in mouse hepatitis coronavirus-infected mice
👤 Raaben, Matthijs 👤 Grinwis, Guy C.M. 👤 Rottier, Peter J.M. 👤 De Haan, Cornelis A.M. ⏰ 2010 📚 Journal of Virology
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Type I interferon receptor-independent and -dependent host transcriptional responses to mouse hepatitis coronavirus infection in vivo
👤 Raaben, Matthijs 👤 Groot Koerkamp, Marian J.A. 👤 Rottier, Peter J.M. 👤 de Haan, Cornelis A.M. ⏰ 2009 📚 BMC Genomics
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Middle East Respiratory Coronavirus Accessory Protein 4a Inhibits PKR-Mediated Antiviral Stress Responses
👤 Rabouw, Huib H. 👤 Langereis, Martijn A. 👤 Knaap, Robert C.M. 👤 Dalebout, Tim J. 👤 Canton, Javier 👤 Sola, Isabel 👤 Enjuanes, Luis 👤 Bredenbeek, Peter J. 👤 Kikkert, Marjolein 👤 de Groot, Raoul J. 👤 van Kuppeveld, Frank J.M. ⏰ 2016 📚 PLoS Pathogens
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Avoiding regions symptomatic of conformational and functional flexibility to identify antiviral targets in current and future coronaviruses
👤 Rahaman, Jordon 👤 Siltberg-Liberles, Jessica ⏰ 2016 📚 Genome Biology and Evolution
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Practical Strategies Against the Novel Coronavirus and COVID-19-the Imminent Global Threat.
👤 Rahimi, Farid 👤 Talebi Bezmin Abadi, Amin ⏰ 2020 📚 Arch Med Res
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Severe acute respiratory syndrome coronavirus papain-like-protease: Structure of a viral deubiquitinating enzyme
👤 Ratia, Kiira 👤 Saikatendu, Kumar Singh 👤 Santarsiero, Bernard D. 👤 Barreto, Naina 👤 Baker, Susan C. 👤 Stevens, Raymond C. 👤 Mesecar, Andrew D. ⏰ 2006 📚 Proceedings of the National Academy of Sciences of the United States of America
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Severe acute respiratory syndrome coronaviruses with mutations in the E protein are attenuated and promising vaccine candidates
👤 Regla-Nava, Jose A. 👤 Nieto-Torres, Jose L. 👤 Jimenez-Guardeño, Jose M. 👤 Fernandez-Delgado, Raul 👤 Fett, Craig 👤 Castaño-Rodríguez, Carlos 👤 Perlman, Stanley 👤 Enjuanes, Luis 👤 De Diego, Marta L. ⏰ 2015 📚 Journal of Virology
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Structural Bases of Coronavirus Attachment to Host Aminopeptidase N and Its Inhibition by Neutralizing Antibodies
👤 Reguera, Juan 👤 Santiago, César 👤 Mudgal, Gaurav 👤 Ordoño, Desiderio 👤 Enjuanes, Luis 👤 Casasnovas, José M. ⏰ 2012 📚 PLoS Pathogens
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[Remdesivir, the antiviral hope against SARS-CoV-2].
👤 Reina, J ⏰ 2020 📚 Rev Esp Quimioter
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Apoptosis induced by the SARS-associated coronavirus in vero cells is replication-dependent and involves caspase
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The structure of the endoribonuclease XendoU: From small nucleolar RNA processing to severe acute respiratory syndrome coronavirus replication
👤 Renzi, Fabiana 👤 Caffarelli, Elisa 👤 Laneve, Pietro 👤 Bozzoni, Irene 👤 Brunori, Maurizio 👤 Vallone, Beatrice ⏰ 2006 📚 Proceedings of the National Academy of Sciences of the United States of America
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A mouse-adapted SARS-coronavirus causes disease and mortality in BALB/c mice
👤 Roberts, Anjeanette 👤 Deming, Damon 👤 Paddock, Christopher D. 👤 Cheng, Aaron 👤 Yount, Boyd 👤 Vogel, Leatrice 👤 Herman, Brian D. 👤 Sheahan, Tim 👤 Heise, Mark 👤 Genrich, Gillian L. 👤 Zaki, Sherif R. 👤 Baric, Ralph 👤 Subbarao, Kanta ⏰ 2007 📚 PLoS Pathogens
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Severe acute respiratory syndrome coronavirus infection of Golden Syrian hamsters
👤 Roberts, Anjeanette 👤 Vogel, Leatrice 👤 Guarner, Jeannette 👤 Hayes, Norman 👤 Murphy, Brian 👤 Zaki, Sherif 👤 Subbarao, Kanta ⏰ 2005 📚 Journal of Virology
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Immune responses and pathogenesis of SARS-CoV-2 during an outbreak in Iran: Comparison with SARS and MERS.
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Practical indications for the prevention and management of SARS-CoV-2 in ambulatory dialysis patients: lessons from the first phase of the epidemics in Lombardy.
👤 Rombola, Giuseppe 👤 Heidempergher, Marco 👤 Pedrini, Luciano 👤 Farina, Marco 👤 Aucella, Filippo 👤 Messa, Piergiorgio 👤 Brunori, Giuliano ⏰ 2020 📚 J Nephrol
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Murine coronavirus delays expression of a subset of interferon-stimulated genes
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Nitazoxanide, a new drug candidate for the treatment of Middle East respiratory syndrome coronavirus
👤 Rossignol, Jean François ⏰ 2016 📚 Journal of Infection and Public Health
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Lianhuaqingwen exerts anti-viral and anti-inflammatory activity against novel coronavirus (SARS-CoV-2).
👤 Runfeng, Li 👤 Yunlong, Hou 👤 Jicheng, Huang 👤 Weiqi, Pan 👤 Qinhai, Ma 👤 Yongxia, Shi 👤 Chufang, Li 👤 Jin, Zhao 👤 Zhenhua, Jia 👤 Haiming, Jiang 👤 Kui, Zheng 👤 Shuxiang, Huang 👤 Jun, Dai 👤 Xiaobo, Li 👤 Xiaotao, Hou 👤 Lin, Wang 👤 Nanshan, Zhong 👤 Zifeng, Yang ⏰ 2020 📚 Pharmacol Res
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Inhibition of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) infectivity by peptides analogous to the viral spike protein
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Two-amino acids change in the nsp4 of SARS coronavirus abolishes viral replication
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Memory CD4+ T-cell-mediated protection from lethal coronavirus encephalomyelitis
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The synergistic interaction of interferon types I and II leads to marked reduction in severe acute respiratory syndrome-associated coronavirus replication and increase in the expression of mRNAs for interferon-induced proteins
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Severe acute respiratory syndrome coronavirus elicits a weak interferon response compared to traditional interferon-inducing viruses
👤 Scagnolari, Carolina 👤 Trombetti, Simona 👤 Cicetti, Simona 👤 Antonelli, Silvia 👤 Selvaggi, Carla 👤 Perrone, Lorena 👤 Visca, Michela 👤 Romano, Sara 👤 Antonelli, Guido ⏰ 2008 📚 Intervirology
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Kaempferol derivatives as antiviral drugs against the 3a channel protein of coronavirus
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Emodin inhibits current through SARS-associated coronavirus 3a protein
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Characterization and application of monoclonal antibodies against N protein of SARS-coronavirus
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The outbreak of SARS-CoV-2 pneumonia calls for viral vaccines.
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An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice.
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TMPRSS2: A potential target for treatment of influenza virus and coronavirus infections
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Safe and sensitive antiviral screening platform based on recombinant human coronavirus OC43 expressing the luciferase reporter gene
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A conserved region of nonstructural protein 1 from alphacoronaviruses inhibits host gene expression and is critical for viral virulence
👤 Shen, Zhou 👤 Wang, Gang 👤 Yang, Yiling 👤 Shi, Jiale 👤 Fang, Liurong 👤 Li, Fang 👤 Xiao, Shaobo 👤 Fu, Zhen F. 👤 Peng, Guiqing ⏰ 2019 📚 Journal of Biological Chemistry
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SARS Coronavirus Fusion Peptide-Derived Sequence Suppresses Collagen-Induced Arthritis in DBA/1J Mice
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👤 Shereen, Muhammad Adnan 👤 Khan, Suliman 👤 Kazmi, Abeer 👤 Bashir, Nadia 👤 Siddique, Rabeea ⏰ 2020 📚 J Adv Res
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SARS-coronavirus open reading frame-9b suppresses innate immunity by targeting mitochondria and the MAVS/TRAF3/TRAF6 signalosome
👤 Shi, Chong Shan 👤 Qi, Hai Yan 👤 Boularan, Cedric 👤 Huang, Ning Na 👤 Abu-Asab, Mones 👤 Shelhamer, James H. 👤 Kehrl, John H. ⏰ 2014 📚 Journal of Immunology
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Saracatinib inhibits middle east respiratory syndrome-coronavirus replication in vitro
👤 Shin, Jin Soo 👤 Jung, Eunhye 👤 Kim, Meehyein 👤 Baric, Ralph S. 👤 Go, Yun Young ⏰ 2018 📚 Viruses
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Role of spike protein endodomains in regulating coronavirus entry
👤 Shulla, Ana 👤 Gallagher, Tom ⏰ 2009 📚 Journal of Biological Chemistry
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Proteolytic activation of the SARS-coronavirus spike protein: Cutting enzymes at the cutting edge of antiviral research
👤 Simmons, Graham 👤 Zmora, Pawel 👤 Gierer, Stefanie 👤 Heurich, Adeline 👤 Pöhlmann, Stefan ⏰ 2013 📚 Antiviral Research
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Proteolytic activation of the SARS-coronavirus spike protein: Cutting enzymes at the cutting edge of antiviral research
👤 Simmons, Graham 👤 Zmora, Pawel 👤 Gierer, Stefanie 👤 Heurich, Adeline 👤 Pöhlmann, Stefan ⏰ 2013 📚 Antiviral Research
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Release of severe acute respiratory syndrome coronavirus nuclear import block enhances host transcription in human lung cells
👤 Sims, Amy C. 👤 Tilton, Susan C. 👤 Menachery, Vineet D. 👤 Gralinski, Lisa E. 👤 Schäfer, Alexandra 👤 Matzke, Melissa M. 👤 Webb-Robertson, Bobbie Jo M. 👤 Chang, Jean 👤 Luna, Maria L. 👤 Long, Casey E. 👤 Shukla, Anil K. 👤 Bankhead III, Armand R. 👤 Burkett, Susan E. 👤 Zornetzer, Gregory 👤 Tseng, Chien Te Kent 👤 Metz, Thomas O. 👤 Pickles, Raymond 👤 McWeeney, Shannon 👤 Smith, Richard D. 👤 Katze, Michael G. 👤 Waters, Katrina M. 👤 Barica, Ralph S. ⏰ 2013 📚 Journal of Virology
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Suppression of innate antiviral response by severe acute respiratory syndrome coronavirus M protein is mediated through the first transmembrane domain
👤 Siu, Kam Leung 👤 Chan, Chi Ping 👤 Kok, Kin Hang 👤 Chiu-Yat Woo, Patrick 👤 Jin, Dong Yan ⏰ 2014 📚 Cellular and Molecular Immunology
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Middle east respiratory syndrome coronavirus 4a protein is a double-stranded RNA-binding protein that suppresses PACT-induced activation of RIG-I and MDA5 in the innate antiviral response
👤 Siu, Kam Leung 👤 Yeung, Man Lung 👤 Kok, Kin Hang 👤 Yuen, Kit San 👤 Kew, Chun 👤 Lui, Pak Yin 👤 Chan, Chi Ping 👤 Tse, Herman 👤 Woo, Patrick C.Y. 👤 Yuen, Kwok Yung 👤 Jin, Dong Yan ⏰ 2014 📚 Journal of Virology
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Chemokine CXCL10 and Coronavirus-Induced Neurologic Disease
👤 Skinner, Dominic 👤 Marro, Brett S. 👤 Lane, Thomas E. ⏰ 2019 📚 Viral Immunology
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Coronaviruses Lacking Exoribonuclease Activity Are Susceptible to Lethal Mutagenesis: Evidence for Proofreading and Potential Therapeutics
👤 Smith, Everett Clinton 👤 Blanc, Hervé 👤 Vignuzzi, Marco 👤 Denison, Mark R. ⏰ 2013 📚 PLoS Pathogens
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Unique and conserved features of genome and proteome of SARS-coronavirus, an early split-off from the coronavirus group 2 lineage
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The antiviral effect of interferon-beta against SARS-Coronavirus is not mediated by MxA protein
👤 Spiegel, Martin 👤 Pichlmair, Andreas 👤 Mühlberger, Elke 👤 Haller, Otto 👤 Weber, Friedemann ⏰ 2004 📚 Journal of Clinical Virology
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Structural Genomics of SARS-CoV-2 Indicates Evolutionary Conserved Functional Regions of Viral Proteins.
👤 Srinivasan, Suhas 👤 Cui, Hongzhu 👤 Gao, Ziyang 👤 Liu, Ming 👤 Lu, Senbao 👤 Mkandawire, Winnie 👤 Narykov, Oleksandr 👤 Sun, Mo 👤 Korkin, Dmitry ⏰ 2020 📚 Viruses
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Targeting zoonotic viruses: Structure-based inhibition of the 3C-like protease from bat coronavirus HKU4 - The likely reservoir host to the human coronavirus that causes Middle East Respiratory Syndrome (MERS)
👤 St. John, Sarah E. 👤 Tomar, Sakshi 👤 Stauffer, Shaun R. 👤 Mesecar, Andrew D. ⏰ 2015 📚 Bioorganic and Medicinal Chemistry
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Amiodarone alters late endosomes and inhibits SARS coronavirus infection at a post-endosomal level
👤 Stadler, Konrad 👤 Ha, Huy Riem 👤 Ciminale, Vincenzo 👤 Spirli, Carlo 👤 Saletti, Giulietta 👤 Schiavon, Marco 👤 Bruttomesso, Daniela 👤 Bigler, Laurent 👤 Follath, Ferenc 👤 Pettenazzo, Andrea 👤 Baritussio, Aldo ⏰ 2008 📚 American Journal of Respiratory Cell and Molecular Biology
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An atypical RNA pseudoknot stimulator and an upstream attenuation signal for -1 ribosomal frameshifting of SARS coronavirus
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Potent neutralization of severe acute respiratory syndrome (SARS) coronavirus by a human mAb to S1 protein that blocks receptor association
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Coronavirus papain-like proteases negatively regulate antiviral innate immune response through disruption of STING-mediated signaling
👤 Sun, Li 👤 Xing, Yaling 👤 Chen, Xiaojuan 👤 Zheng, Yang 👤 Yang, Yudong 👤 Nichols, Daniel B. 👤 Clementz, Mark A. 👤 Banach, Bridget S. 👤 Li, Kui 👤 Baker, Susan C. 👤 Chen, Zhongbin ⏰ 2012 📚 PLoS ONE
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Identification of a novel inhibitor against middle east respiratory syndrome coronavirus
👤 Sun, Yaping 👤 Zhang, Huaidong 👤 Shi, Jian 👤 Zhang, Zhe 👤 Gong, Rui ⏰ 2017 📚 Viruses
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Epitope-based peptide vaccine design and target site depiction against Middle East Respiratory Syndrome Coronavirus: An immune-informatics study
👤 Tahir Ul Qamar, Muhammad 👤 Saleem, Saman 👤 Ashfaq, Usman Ali 👤 Bari, Amna 👤 Anwar, Farooq 👤 Alqahtani, Safar ⏰ 2019 📚 Journal of Translational Medicine
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Antiviral activity of itraconazole against type i feline coronavirus infection
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The cholesterol transport inhibitor U18666A inhibits type I feline coronavirus infection
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Differential effect of cholesterol on type I and II feline coronavirus infection
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Inhibition of SARS Coronavirus Infection in Vitro with Clinically Approved Antiviral Drugs
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Regulation of cell death during infection by the severe acute respiratory syndrome coronavirus and other coronaviruses
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Comparison of Hospitalized Patients with Acute Respiratory Distress Syndrome Caused by COVID-19 and H1N1.
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The adamantane-derived bananins are potent inhibitors of the helicase activities and replication of SARS coronavirus
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Characterization and demonstration of the value of a lethal mouse model of Middle East respiratory syndrome coronavirus infection and disease
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Severe acute respiratory syndrome coronavirus ORF7a inhibits bone marrow stromal antigen 2 virion tethering through a novel mechanism of glycosylation interference
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Multisite inhibitors for enteric coronavirus: antiviral cationic carbon dots based on curcumin
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